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“Risa”
MRA HJ’s Risa Evee on the Eyes

Australian Shepherd Group

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Place of Birth

Aynor, SC, USA

From

Aynor, SC, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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Genetic Stats

Predicted Adult Weight

56 lbs

Genetic Age
10 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Australian Shepherd

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Changes to this dog’s profile
  • On 4/29/2022 changed name from "Rise" to "MRA HJ’s Risa Evee on the Eyes"

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Health Summary

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Risa is at increased risk for one genetic health condition.

Multiple Drug Sensitivity

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Risa inherited one copy of the variant we tested

How to interpret this result

Risa has one copy of a variant at the ABCB1 gene and is at risk for displaying adverse drug reactions. While she may not be as severely affected as a dog with two copies of the ABCB1 drug sensitivity allele, normal dosages of drugs could still have potentially severe effects on Risa. Please inform your veterinarian that Risa carries this variant; it is essential that they know this information before prescribing drugs.

What is Multiple Drug Sensitivity?

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with a mutation in the ABCB1 gene.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Australian Shepherds and Australian Shepherds

Collie Eye Anomaly (NHEJ1)

Identified in Australian Shepherds and Australian Shepherds

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Australian Shepherds and Australian Shepherds

Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Australian Shepherds and Australian Shepherds

Hereditary Cataracts (HSF4 Exon 9, Australian Shepherd Variant)

Identified in Australian Shepherds and Australian Shepherds

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Australian Shepherds and Australian Shepherds

Neuronal Ceroid Lipofuscinosis 6, NCL 6 (CLN6 Exon 7, Australian Shepherd Variant)

Identified in Australian Shepherds and Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)

Identified in Australian Shepherds and Australian Shepherds

Craniomandibular Osteopathy, CMO (SLC37A2)

Identified in Australian Shepherds and Australian Shepherds

Additional Genetic Conditions

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Clinical Tools

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Risa’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B81

Map

B1

MRA HJ’s Risa Evee on the Eyes’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B81

MRA HJ’s Risa Evee on the Eyes’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most frequently in Shih Tzus, Chihuahuas, and Poodles.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Risa inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Risa is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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