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“Sweets”
Riding a Sweet Wind of Columbia Gorge Cotons

Coton de Tulear

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Registration

Malagasy Coton de Tulear Preservation Club (MCPC):

Genetic Breed Result

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Coton de Tulear

The Coton de Tulear is a smaller breed with a cotton-like coat and lovable personality. They come from Madagascar, where they have been everything from pets of the royal family to free-ranging street dogs. They’re known as the “Royal Dog of Madagascar” and have been honored as such on a postage stamp.

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Here’s what Sweets’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Sweets’s breed mix.
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Health Summary

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Sweets has one variant that you should let your vet know about.

ALT Activity

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Sweets inherited one copy of the variant we tested

Why is this important to your vet?

Sweets has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sweets has this genotype, as ALT is often used as an indicator of liver health and Sweets is likely to have a lower than average resting ALT activity. As such, an increase in Sweets’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Coton de Tulears

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Coton de Tulears

Canine Multifocal Retinopathy, cmr2 (BEST1 Exon 5, Coton de Tulear Variant)

Identified in Coton de Tulears

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Coton de Tulears

Primary Hyperoxaluria (AGXT)

Identified in Coton de Tulears

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Coton de Tulears

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Sweets’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1/13

Map

B1

Riding a Sweet Wind of Columbia Gorge Cotons’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1/13

Riding a Sweet Wind of Columbia Gorge Cotons’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in Shih Tzus, Tibetan Spaniels, Maltese, and village dogs throughout the world including Central and South America, South Asia, and the South Pacific.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Sweets inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Sweets is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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