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Renegade

Mixed Ancestry

“Renegade was adopted 6 years ago at the SPCA in Lake Jackson, TX. He joined our family at Christmas”

Current Location

Lake Jackson, Texas, USA

From

SPCA of Brazoria County, Canna Lane, Lake Jackson, TX, USA

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Weimaraner

The Weimaraner is an all-purpose gun dog. The name comes from the Grand Duke of Saxe-Weimar-Eisenach, Karl August, whose court, based in the city of Weimar (now in the state of Thuringia in modern-day Germany), enjoyed hunting.

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Bluetick Coonhound

Bluetick Coonhounds are an American breed of hound that originated in the Southern United States, which is a pretty common story for American breeds, particularly hounds. While they can make good house dogs, Bluetick Coonhounds are still mostly hunting dogs.

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Chinese Shar-Pei

Few dog breeds are more recognizable than the wrinkly Chinese Shar-Pei. This Chinese breed is often compared to a hippopotamus due to its thick muzzle. They also have a characteristic rough, bristly coat, which is how the breed got its name (“Shar-Pei” means “sand skin”). Despite their goofy appearance, Shar-Peis are serious, independent dogs who will loyally protect their owners.

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American Staffordshire Terrier

American Staffordshire Terriers are powerful but playful dogs that are both loyal and affectionate with their owners.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Keeshond

The Keeshond is one of the friendliest dogs out there. They appear to have a permenant smile on their face. They were originally bred as watchdogs in Holland, but now serve a lovable companions in the home.

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Dogs Like Renegade

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Discover dogs who share a similar breed mix to Renegade. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Weimaraner
Bluetick Coonhound
Chinese Shar-Pei
American Staffordshire Terrier
Labrador Retriever
Keeshond
Supermutt

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Here’s what Renegade’s family tree may have looked like.
Renegade
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Weimaraner mix Chinese Shar-Pei / Labrador Retriever mix American Staffordshire Terrier / Keeshond mix Weimaraner Bluetick Coonhound mix Chinese Shar-Pei Labrador Retriever mix American Staffordshire Terrier mix Keeshond mix Weimaraner Weimaraner Bluetick Coonhound Bluetick Coonhound mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Renegade’s breed mix.
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Health Summary

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Renegade is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever

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Renegade inherited one copy of the variant we tested

How to interpret this result

Renegade has one copy of a variant in the MTBP gene and is considered at risk for developing SPAID. More commonly known as Familial Shar-Pei Fever, this condition causes recurrent high fevers and joint swelling and pain. Some Shar-Peis will also develop an inappropriate accumulation of protein in the liver and kidneys. This variant likely has an incomplete dominant inheritance in the Shar-Pei, meaning that Shar-Peis with one copy of the variant are at lower risk when compared to dogs with two copies of the variant, but at greater risk than dogs with no copies of the variant. Please consult with your veterinarian to discuss further diagnostic, treatment, and monitoring options for Renegade.

What is Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever?

More commonly known as Familial Shar-Pei Fever, this autoinflammatory condition causes recurrent high fevers, joint swelling and pain, and overall malaise. Some Shar-Peis will also develop amyloidosis, an inappropriate accumulation of an abnormal protein, amyloid, in the liver and kidneys.

Urate Kidney & Bladder Stones

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Renegade inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Renegade’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Renegade is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

ALT Activity

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Renegade inherited one copy of the variant we tested

Why is this important to your vet?

Renegade has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Renegade has this genotype, as ALT is often used as an indicator of liver health and Renegade is likely to have a lower than average resting ALT activity. As such, an increase in Renegade’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd1

Identified in American Staffordshire Terriers

Progressive Retinal Atrophy, crd2

Identified in American Staffordshire Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Day Blindness

Identified in Labrador Retrievers

Primary Open Angle Glaucoma and Primary Lens Luxation

Identified in Chinese Shar-Peis

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Staffordshire Terriers

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in Labrador Retrievers

Hypomyelination and Tremors

Identified in Weimaraners

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Staffordshire Terriers

Narcolepsy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Renegade’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B77

Map

B1

Renegade’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B77

Renegade’s Haplotype

Part of the B1 haplogroup, this haplotype occurs most frequently in Japanese Chins.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Renegade’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.6

Map

A1a

Renegade’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.6

Renegade’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in Labrador Retrievers, Basset Hounds, and Leonbergers, and village dogs in Fiji.

Dogs with A1a lineage travelled during European Colonial times.

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