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Reggie

Pomeranian

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Genetic Breed Result

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Genetic Stats

Predicted Adult Weight

7 lbs

Genetic Age
26 human years

Based on the date of birth provided

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Reggie’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Reggie inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Reggie inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Reggie is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Reggie inherited both copies of the variant we tested

Why is this important to your vet?

Reggie has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Reggie's ALT activity above their current, healthy, ALT activity. As an increase above Reggie’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Methemoglobinemia (CYB5R3)

Identified in Pomeranians

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Pomeranians

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Reggie’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C18

Map

C2

Reggie’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C18

Reggie’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most commonly in Nova Scotia Duck Tolling Retrievers, Pomeranians, and Chihuahuas.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

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Through Reggie’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.44

Map

A1b

Reggie’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.44

Reggie’s Haplotype

Part of the A1b haplogroup, this haplotype occurs primarily in Poodles and Belgian Sheepdogs.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

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