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Rambo

Boerboel

“Rambo was born on July 4th 2020. My mom got him from a family friend as a gift to give to me in effort to cheer me up after I had a really bad car accident while on active duty in the Air Force. He is as wild and exciting as the holiday! He loves to play and wrestle and loves his walks! Although he is big in size, he has an even bigger heart. He loves Jeep rides! My 11 and 6 years old daughters are absolutely nuts about our nut, Rambo! What a teddy bear he is! 100%dog×100%Amazing= 1000% Rambo”

Place of Birth

Chicago, Illinois, USA

Current Location

Tucson, Arizona, USA

This dog has been viewed and been given 4 wags

Registration

American Kennel Club (AKC): 14684970

Genetic Breed Result

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Boerboel

Bred as a farming dog in South Africa, this breed had to be tough to survive harsh conditions and predators. But these thick-necked protectors are generally calm, so long as they can get some exercise. They are known for being great with kids and families, but you should have a dominant personality or they may be taking you for a walk instead of the other way around.

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Here’s what Rambo’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Rambo’s breed mix.

Breed Reveal Video

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Health Summary

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Rambo inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Canine Multifocal Retinopathy, cmr1

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Rambo inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Rambo’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Rambo is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

This result is also important if you decide to breed this dog - to produce the healthiest puppies we recommend genetic testing any potential mates for this condition.

What is Canine Multifocal Retinopathy, cmr1?

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. Dogs with larger lesions can suffer from vision loss. CMR is fairly non-progressive; new lesions will typically stop forming by the time a dog is an adult, and some lesions will even regress with time.

ALT Activity

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Rambo inherited one copy of the variant we tested

Why is this important to your vet?

Rambo has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Rambo has this genotype, as ALT is often used as an indicator of liver health and Rambo is likely to have a lower than average resting ALT activity. As such, an increase in Rambo’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Urate Kidney & Bladder Stones

Identified in Boerboels

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Rambo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A393/A559

Map

A1a

Rambo’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A393/A559

Rambo’s Haplotype

Part of the A1a haplogroup, the A393/A559 haplotype occurs most frequently in Yorkshire Terriers, Russell-type Terriers, and Tibetan Terriers.

Shar Pei dogs think A1a is the coolest!

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Through Rambo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

H3

Map

A2b

Rambo’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

H3

Rambo’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most commonly in Cavalier King Charles Spaniels, Brittanys, Soft Coated Wheaten Terriers, and village dogs in Lebanon.

A2b is found in the Daschund breed.

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