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Quinn

Sheepadoodle

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“Quirky Panda looking Sheepadoodle”

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Genetic Breed Result

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Old English Sheepdog

The Old English Sheepdog is a spirited breed that likes to show of its working ability and that amazing shaggy coat. These guys have been around since the early 1800's and are still best used as herding dogs. They can make great family pets as long as you are ready to fill their exercise and grooming needs.

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Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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DNA Breed Origins

Breed colors:
Old English Sheepdog
Poodle (Standard)

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Quinn’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Quinn inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Quinn inherited one copy of the variant we tested

What does this result mean?

This result should not impact Quinn’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Quinn inherited one copy of the variant we tested

Why is this important to your vet?

Quinn has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Quinn has this genotype, as ALT is often used as an indicator of liver health and Quinn is likely to have a lower than average resting ALT activity. As such, an increase in Quinn’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Old English Sheepdogs

Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Standard Poodles

Primary Ciliary Dyskinesia, PCD (CCDC39 Exon 3, Old English Sheepdog Variant)

Identified in Old English Sheepdogs

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Hereditary Ataxia, Cerebellar Degeneration (RAB24, Old English Sheepdog and Gordon Setter Variant)

Identified in Old English Sheepdogs

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Exercise-Induced Collapse, EIC (DNM1)

Identified in Old English Sheepdogs

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Quinn’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Quinn’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Quinn’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Quinn inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Quinn is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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