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“Hemi”
CH 'PR' Coldwater Loose 'Cuda O'Sands

Rat Terrier

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“Hemi is an impressive girl with black tricolor markings, gorgeous standing ears and a docked tail. She weighs 22lb and stands 16" at the shoulder. She has a spunky, highly affectionate personality and loves the company of other dogs and all people. Hemi is a show champion from a long line of show champions. She is now working on her grand title. She will also be CHIC certified by OFA as age requirements are met. We look forward to Hemi making one marvelous, healthy contribution to her breed!”

Place of Birth

Stokesdale, NC, USA

Current Location

Glennville, GA, USA

From

Stokesdale, NC, USA

This dog has been viewed and been given 1 wag

Registration

American Kennel Club (AKC): RN35765602
Microchip: 956000013484290

Genetic Breed Result

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Rat Terrier

The Rat Terrier is an American dog breed with a background as a farm dog and hunting companion.

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Changes to this dog’s profile
  • On 1/14/2021 changed name from "'PR' Coldwater Loose 'Cuda O'Sands" to "Coldwater Loose 'Cuda O'Sands"

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Health Summary

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Hemi inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Dilated Cardiomyopathy, DCM2

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Hemi inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Hemi will develop this condition.

Scientific Basis

Dogs with Hemi’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Hemi developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Hemi inherited one copy of the variant we tested

Why is this important to your vet?

Hemi has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Hemi has this genotype, as ALT is often used as an indicator of liver health and Hemi is likely to have a lower than average resting ALT activity. As such, an increase in Hemi’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Congenital Hypothyroidism (TPO, Rat, Toy, Hairless Terrier Variant)

Identified in Rat Terriers

Primary Lens Luxation (ADAMTS17)

Identified in Rat Terriers

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Hemi’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C42/54/55

Map

C2

Coldwater Loose 'Cuda O'Sands’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C42/54/55

Coldwater Loose 'Cuda O'Sands’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Hemi inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Hemi is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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