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“Zeppelin”
PookaxDaisy's Goofy

Pomsky

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Place of Birth

Roseburg, Oregon, USA

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Genetic Breed Result

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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DNA Breed Origins

Breed colors:
Pomeranian
Siberian Husky

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Health Summary

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Zeppelin inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Copper Toxicosis (Accumulating)

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Zeppelin inherited one copy of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Zeppelin will develop Copper Toxicosis (Accumulating).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Zeppelin's breed have been studied to know whether or not this variant will increase Zeppelin's risk of developing this disease.

Impact on Breeding

Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Copper Toxicosis (Accumulating) in your breeding program and related dogs.

What is Copper Toxicosis (Accumulating)?

Copper toxicosis is a condition in which affected dogs have difficulty excreting excess copper from their liver. The liver accumulates more copper until it eventually begins failing. Multiple genetic and environmental factors contribute to the development of this condition.

ALT Activity

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Zeppelin inherited one copy of the variant we tested

Why is this important to your vet?

Zeppelin has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Zeppelin has this genotype, as ALT is often used as an indicator of liver health and Zeppelin is likely to have a lower than average resting ALT activity. As such, an increase in Zeppelin’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Methemoglobinemia (CYB5R3)

Identified in Pomeranians

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Pomeranians

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Siberian Huskies

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in Siberian Huskies

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Progressive Retinal Atrophy 5, PRA5 (NECAP1 Exon 6, Giant Schnauzer Variant)

Identified in Pomeranians

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Zeppelin’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A405

Map

A1b

PookaxDaisy's Goofy’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A405

PookaxDaisy's Goofy’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in mixed breed dogs.

A1b is the most common haplogroup found in German Shepherds.

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Through Zeppelin’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.44

Map

A1b

PookaxDaisy's Goofy’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.44

PookaxDaisy's Goofy’s Haplotype

Part of the A1b haplogroup, this haplotype occurs primarily in Poodles and Belgian Sheepdogs.

Great Danes and Pomeranians have this in common!

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