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“Vistonic”
Points Unknown's Vistonic

Alaskan-type Husky

“1/2 Hedlund Husky - rare line of Traditional Alaskan (Husky) Village Dog and half Bassich/Calico lines - Traditional Alaskan (Husky) Village Dog”

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Genetic Breed Result

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What exactly are village dogs?

Village dogs are the free-breeding, free-roaming “outside” dogs found around the world living in and around human settlements big and small. They are also known as island dogs, pariah dogs, or free-ranging dogs.

Many village dog populations precede the formation of modern breed dogs.

They make up about 3/4s of the billion or so dogs living on Earth today. They serve as trash cleaners, sentinels, and even sometimes companions while still retaining much of their freedom. Embark’s founders have studied village dogs on six continents since 2007 in their efforts to understand the history, traits, and health of the domestic dog. Through this work they have discovered the origins of the dog in Central Asia, and also identified genetic regions involved in domestication and local adaptation, such as the high altitude adaptation in Himalayan dogs. Embark is the only dog DNA test that includes diverse village dogs from around the world in its breed reference panel.

So what breeds are in my dog?

In a very real sense, Alaskan-type Husky is the actual breed of your dog. Village dogs like this descend from separate lines of dogs than the lines that have been bred into standardized breeds like Labradors and Poodles. If you trace the family tree of Vistonic back, you won’t find any ancestral dogs that are part of any of those standardized breeds.

Alaskan-type Husky

The Alaskan Husky is all athlete. These dogs have a wide variety of appearances because they are bred for performance and behavior rather than looks. In fact, they've been specifically bred to pull sleds for hundreds of years. In temperament, they tend to be similar to the Siberian Husky.

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Village dogs have lived just about everywhere across the world for thousands of years. Long before there were any recognized dog breeds, there were village dogs around the fires and trash heaps of early human villages. Vistonic is part of this ancient heritage, not descended from a specific breed, but continuing the ancient lineage of dogs that were our first, best friends.

Embark's co-founders studied Village Dogs on six continents in their efforts to understand the history, traits, and health of the domestic dog. Through this work, they discovered evidence for the origins of the dog in Central Asia , and they also identified genetic regions involved in domestication and local adaptation. As a result, Embark has the largest Village Dog reference panel of any canine genetics company.

We compared Vistonic's DNA to a global panel of thousands of village dogs. This plot highlights regions of the world where Vistonic's DNA is most similar to those village dogs. The areas of darkest red reflect the greatest similarity to our village dog panel.

Village Dog Map
Similarity to village dog groups around the world. Darker red reflects greater similarity.

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Health Summary

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Vistonic inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Vistonic inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Vistonic’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Vistonic is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Vistonic inherited both copies of the variant we tested

Why is this important to your vet?

Vistonic has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Vistonic's ALT activity above their current, healthy, ALT activity. As an increase above Vistonic’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Alaskan Husky Encephalopathy (SLC19A3)

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Vistonic’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A11a

Map

A1d

Points Unknown's Vistonic’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A11a

Points Unknown's Vistonic’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 23 breeds we have sampled it in, the most common occurrences include Rottweilers, English Setters, English Springer Spaniels, and wirehaired pointing griffons.

The vast majority of Rottweilers have the A1d haplogroup.

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Through Vistonic’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A

Haplotype

Hc.1

Map

A

Points Unknown's Vistonic’s Haplogroup

A is the distant relative of some of the most numerous paternal lineages in the world. Characterized by a single sub-lineage, this is a rare and interesting paternal line! The A line is found most commonly in Siberian Huskies and in Alaskan village dogs. It seems plausible that this paternal lineage diverged within the last 10,000 years from a group arriving with the first Arctic explorers. The recent ancestors of dogs with this lineage actually allowed humans to survive in some of the most forbidding conditions on the face of the earth!

Hc.1

Points Unknown's Vistonic’s Haplotype

The lone member of the A haplogroup, this haplotype occurs most commonly in Siberian Huskies and village dogs from Alaska.

Siberian Huskys are the only breed to have the A haplogroup.

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