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“Roxy”
PMB's Roxy Rey West

Alapaha Blue Blood Bulldog

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Registration

Alapaha Bulldog Registry (ABR): ABR-03-5312
Microchip: 981020021500996

Genetic Breed Result

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Alapaha Blue Blood Bulldog

The Alapaha Blue Blood Bulldog is a bulldog type breed that was developed in the southern part of the United States as a catch dog.

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Health Summary

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Roxy inherited one variant that you should learn more about.

Dilated Cardiomyopathy, DCM1

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Roxy inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Roxy will develop this condition.

Scientific Basis

Dogs with Roxy’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Roxy developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, crd1 (PDE6B, American Staffordshire Terrier Variant)

Identified in Alapaha Blue Blood Bulldogs

Progressive Retinal Atrophy, crd2 (IQCB1)

Identified in Alapaha Blue Blood Bulldogs

Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Alapaha Blue Blood Bulldogs

Hereditary Cataracts (HSF4 Exon 9, Boston Terrier Variant)

Identified in Alapaha Blue Blood Bulldogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Alapaha Blue Blood Bulldogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A (ARSG Exon 2, American Staffordshire Terrier Variant)

Identified in Alapaha Blue Blood Bulldogs

Neuronal Ceroid Lipofuscinosis 10, NCL 10 (CTSD Exon 5, American Bulldog Variant)

Identified in Alapaha Blue Blood Bulldogs

L-2-Hydroxyglutaricaciduria, L2HGA (L2HGDH, Staffordshire Bull Terrier Variant)

Identified in Alapaha Blue Blood Bulldogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Roxy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C3/14

Map

C2

PMB's Roxy Rey West’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C3/14

PMB's Roxy Rey West’s Haplotype

Part of the C2 haplogroup, this common haplotype occurs most often in English Setters, Cairn Terriers, Labrador Retrievers, and village dogs in Peru, Fiji, and across Africa.

You can often find his haplogroup in the lovable English Bulldog.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Roxy inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Roxy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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