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“Piper”
Go go Piper of Pixie's gems

Biewer Terrier

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Genetic Breed Result

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Biewer Terrier

The Biewer Terrier is one of the smallest Terriers within the Toy Group, only 7-8 inches tall and typically less than 8 pounds. In spite of the small size, the Biewer is known as a robust and athletic dog.

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Changes to this dog’s profile
  • On 11/3/2023 changed name from "Piper" to "Go go Piper of Pixie's gems"

Health Summary

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Piper inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Bald Thigh Syndrome

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Piper inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Piper’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Piper is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Bald Thigh Syndrome?

A cosmetic condition common to sighthounds characterized by hair loss on the thighs. It is caused by a structural abnormality of the hair follicle.

ALT Activity

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Piper inherited both copies of the variant we tested

Why is this important to your vet?

Piper has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Piper's ALT activity above their current, healthy, ALT activity. As an increase above Piper’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Biewer Terriers

Primary Lens Luxation (ADAMTS17)

Identified in Biewer Terriers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Piper’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A271

Map

A1d

Go go Piper of Pixie's gems’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A271

Go go Piper of Pixie's gems’s Haplotype

Part of the large A1d haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, English Springer Spaniels, and village dogs in Colombia.

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Piper inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Piper is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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