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Piper

American Bully

“Piper was rescued from the shelter in Bay City, Michigan, in 2014. They guessed her to be about a year and a half old. Her name was "Cricket." She was the loudest dog in the kennels, all the way at the end, and sounded like a squeaky toy when she barked. I was the third to adopt her. She had been caged most of her life at that point, either in her adopted homes or in the shelter. She's home forever with us now and doesn't ever have to be caged again!♡”

Current Location

Birch Run, Michigan, USA

From

Bay City, MI, USA

This dog has been viewed and been given 125 wags

Genetic Breed Result

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American Bully

The American Bully may look intimidating with its muscular build, but these dogs are bred to be the ideal family or companion dog. This breed is notable for coming in several different size and type varieties, so there's a lot of diversity in their appearance. They're a newer breed, originating in the 80s and 90s in the United States.

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Here’s what Piper’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Piper’s breed mix.

Breed Reveal Video

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Health Summary

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Piper inherited two variants that you should learn more about.

Urate Kidney & Bladder Stones

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Piper inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Piper’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Piper is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

Progressive Retinal Atrophy, crd4/cord1

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Piper inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Piper’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Piper is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, crd1

Identified in American Bullies

Canine Multifocal Retinopathy, cmr1

Identified in American Bullies

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Bullies

Neuronal Ceroid Lipofuscinosis 10, NCL 10

Identified in American Bullies

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Bullies

Ichthyosis

Identified in American Bullies

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Piper’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B84

Map

B1

Piper’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B84

Piper’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most frequently in Golden Retrievers, Beagles, and Staffordshire Terriers.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Piper inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Piper is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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