Pepa inherited both copies of the variant we tested
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Registration
American Kennel Club
(AKC):
RN38807602
Microchip: 956000013820275
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Health Summary
Pepa inherited one variant that you should learn more about.
Degenerative Myelopathy, DM
What does this result mean?
We do not know whether this increases the risk that Pepa will develop Degenerative Myelopathy, DM.
Scientific Basis
Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Pepa's breed have been studied to know whether or not this variant will increase Pepa's risk of developing this disease.
Impact on Breeding
Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Degenerative Myelopathy, DM in your breeding program and related dogs.
What is Degenerative Myelopathy, DM?
The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
Breed-Relevant Genetic Conditions
Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cairn and Norfolk Terrier Variant)
Identified in Norfolk Terriers
Variant not detected
Primary Lens Luxation (ADAMTS17)
Identified in Norfolk Terriers
Variant not detected
Ichthyosis, Epidermolytic Hyperkeratosis (KRT10, Terrier Variant)
Identified in Norfolk Terriers
Variant not detected
Additional Genetic Conditions
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What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.