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“Howie”
HTCH Peaslee's Howell the Good

English Shepherd

“Howie is from the 4th generation of the Shepherd's Way line. He combines strong working drive with a clear head and biddability. Howie has multiple herding titles and earned his herding trial championship at 3 years of age. He is a sweet natured, affectionate dog.”

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Registration

UKC: P764-743

Genetic Breed Result

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English Shepherd

English Shepherd English Shepherd
A farmer's helper, a loyal companion, a child's shadow: The English Shepherd.
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Genetic Stats

Wolfiness: 0.6 % LOW Learn More
Predicted Adult Weight: 46 lbs Learn More
Genetic Age: 40 human years Learn More

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Health

Traits

Maternal Haplotype

Paternal Haplotype

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Summary

0
AT RISK
0
CARRIER
165
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Peaslee's Howell the Good has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinaria…

Not At Risk

Good news! Howie did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Howie does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Howie’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Howie is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Howie tested clear for 6 genetic conditions that are common in his breed.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Collie Eye Anomaly, Choroidal Hypoplasia
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Other Conditions: Clear of 159

Howie is clear of 159 other genetic diseases that Embark tests for.

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Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Ee
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
ayat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
BB

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
TT
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TA
Body Size - GHR (E195K)
AA
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Health

Maternal Haplotype

Paternal Haplotype

Through Howie’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247

Map

A1d

Peaslee's Howell the Good’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247

Peaslee's Howell the Good’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Health

Traits

Paternal Haplotype

Through Howie’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.20

Map

A1a

Peaslee's Howell the Good’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.20

Peaslee's Howell the Good’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in village dogs throughout the world (outside of Asia). It is quite common in breed dogs, occurring frequently in Golden Retrievers, Irish Wolfhounds, Scottish Terriers, Border Collies, and Mastiffs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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Health

Traits

Maternal Haplotype