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Peaches

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Health Summary

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Peaches has one variant that you should let your vet know about.

ALT Activity

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Peaches inherited one copy of the variant we tested

Why is this important to your vet?

Peaches has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Peaches has this genotype, as ALT is often used as an indicator of liver health and Peaches is likely to have a lower than average resting ALT activity. As such, an increase in Peaches’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Bernese Mountain Dogs, Standard Poodles, and more

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Standard Poodles and Small Poodles

Dry Eye Curly Coat Syndrome (FAM83H Exon 5)

Identified in Cavalier King Charles Spaniels

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles and Small Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Bernese Mountain Dogs, Cavalier King Charles Spaniels, and more

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles and Small Poodles

Muscular Dystrophy (DMD, Cavalier King Charles Spaniel Variant 1)

Identified in Cavalier King Charles Spaniels

Episodic Falling Syndrome (BCAN)

Identified in Cavalier King Charles Spaniels

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles and Small Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Cavalier King Charles Spaniels, Standard Poodles, and more

Medium-Chain Acyl-CoA Dehydrogenase Deficiency, MCADD (ACADM, Cavalier King Charles Spaniel Variant)

Identified in Cavalier King Charles Spaniels

Additional Genetic Conditions

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