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“Alfadel”
FCI AKC CGC WAC PAX DEORUM CHARLES (RUSSIA) ATTS TT CGCA

Doberman Pinscher

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  • Photo of Alfadel, a Doberman Pinscher  in Timiryazevskaya, Moscow, Russia Photo of Alfadel, a Doberman Pinscher  in Timiryazevskaya, Moscow, Russia
    2019 2.5 years old

“HEIGHT AT WITHERS IS 27 INCHES . ALFADEL IS A IMPORT FROM RUSSIA . HE LOVES WATCHING ANYTHING WITH HORSES IN IT. HE GETS HIS TOYS AND TAKES THEM TO THE TV TO BEFRIEND THE HORSE . HE LOVES TO LEARN NEW TRICKS AND IS A SOCIAL SPOT LITE . MEANING HE KILLS FOR PUBLIC ATTENTION. HE IS OBSESSED WITH CHILDREN AND OLDER PEOPLE WHO SEE HIM WHEN HES OUT AND ABOUT IN TOWN. THEY STOP AND COME TO SEE HIM AND”

Instagram tag
@julieanndipasqua

Place of Birth

Timiryazevskaya, Moscow, Russia

Current Location

Huntsburg, Ohio, USA

From

Cherry Hill, NJ, USA

This dog has been viewed and been given 21 wags

Registration

American Kennel Club (AKC): WS59206202

Genetic Breed Result

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Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

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Genetic Stats

Predicted Adult Weight

82 lbs

Genetic Age
51 human years

Based on the date of birth provided

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Health Summary

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Alfadel is at increased risk for two genetic health conditions.

Dilated Cardiomyopathy, DCM1

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Alfadel inherited one copy of the variant we tested

How to interpret this result

Alfadel has one copy of a variant in the PDK4 gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM1, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Alfadel shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Alfadel.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Dilated Cardiomyopathy, DCM2

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Alfadel inherited one copy of the variant we tested

How to interpret this result

Alfadel has one copy of a variant in the TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Alfadel shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Alfadel.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Doberman Pinschers

Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS (MYO7A)

Identified in Doberman Pinschers

Additional Genetic Conditions

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Clinical Tools

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (EE)
K Locus (CBD103)
More likely to have a patterned haircoat (kyky)
Intensity Loci LINKAGE
Any light hair likely yellow or tan (Intermediate Red Pigmentation)
A Locus (ASIP)
Black/Brown and tan coat color pattern (atat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (Dd)
B Locus (TYRP1)
Black or gray hair and skin (BB)
Saddle Tan (RALY)
Not saddle tan patterned (II)
S Locus (MITF)
Likely to have little to no white in coat (SS)
M Locus (PMEL)
No merle alleles (mm)
H Locus (Harlequin)
No harlequin alleles (hh)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Larger (NN)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)
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Through Alfadel’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C38

Map

C1

PAX DEORUM CHARLES (RUSSIA)’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C38

PAX DEORUM CHARLES (RUSSIA)’s Haplotype

Part of the C1 haplogroup, this haplotype occurs most frequently in Doberman Pinschers and Black Russian Terriers.

Some other Embark dogs with this haplotype:

The C1 maternal line is commonly found in Jackals.

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Through Alfadel’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.13

Map

A1b

PAX DEORUM CHARLES (RUSSIA)’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.13

PAX DEORUM CHARLES (RUSSIA)’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in Doberman Pinschers.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

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