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Otis

Cavapoo

No bio has been provided yet

Place of Birth

Santa Rosa, CA, USA

Current Location

Petaluma, California, USA

From

Santa Rosa, CA, USA

This dog has been viewed and been given 48 wags

Registration

Microchip: 985112008794917

Genetic Breed Result

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Cavalier King Charles Spaniel

The Cavalier King Charles Spaniel is an indoor companion that loves people and should not be left alone for long. They're loved for their sweet temperaments, and make wonderful dogs for families with children or anyone looking for a dog who will stick to them like Velcro.

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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Dogs Like Otis

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Discover dogs who share a similar breed mix to Otis. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Cavalier King Charles Spaniel
Poodle (Small)

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Changes to this dog’s profile
  • On 11/16/2018 changed handle from "otis69" to "otis2118"
Here’s what Otis’s family tree may have looked like.
Otis
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Cavalier King Charles Spaniel mix Poodle (Small) mix Cavalier King Charles Spaniel Cavalier King Charles Spaniel / Poodle (Small) mix Poodle (Small) Cavalier King Charles Spaniel mix Cavalier King Charles Spaniel Cavalier King Charles Spaniel Cavalier King Charles Spaniel Poodle (Small) mix Poodle (Small) Poodle (Small) Cavalier King Charles Spaniel Cavalier King Charles Spaniel mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Otis’s breed mix.
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Health Summary

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Otis is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Otis inherited one copy of the variant we tested

How to interpret this result

Otis has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Degenerative Myelopathy, DM

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Otis inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Otis’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Otis is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Otis inherited one copy of the variant we tested

Why is this important to your vet?

Otis has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Otis has this genotype, as ALT is often used as an indicator of liver health and Otis is likely to have a lower than average resting ALT activity. As such, an increase in Otis’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd

Identified in Small Poodles

Dry Eye Curly Coat Syndrome

Identified in Cavalier King Charles Spaniels

GM2 Gangliosidosis

Identified in Small Poodles

Neonatal Encephalopathy with Seizures, NEWS

Identified in Small Poodles

Muscular Dystrophy

Identified in Cavalier King Charles Spaniels

Episodic Falling Syndrome

Identified in Cavalier King Charles Spaniels

Osteochondrodysplasia

Identified in Small Poodles

Intervertebral Disc Disease (Type I)

Identified in Cavalier King Charles Spaniels and Small Poodles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Otis’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A224

Map

A1a

Otis’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A224

Otis’s Haplotype

Part of the large A1a haplogroup, this haplotype is found in village dogs in Peru, Fiji, and Namibia. Among breeds, we see this haplotype most frequently in Cavalier King Charles Spaniels, Mastiffs, and Boston Terriers.

Shar Pei dogs think A1a is the coolest!

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Through Otis’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.7

Map

A1b

Otis’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.7

Otis’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs from Lebanon and Indonesia. Among breeds, it is also found in Miniature Schnauzer and Toy Poodle.

Great Danes and Pomeranians have this in common!

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