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Orion Black Benoit

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“He’s intelligent, curious, mischievous, social, slightly self-centered, goofy and an absolute sweetheart. Orion is our bratty “middle child” who we couldn’t picture life without.”

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Genetic Breed Result

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39.5% German Shepherd Dog
21.9% Gray Wolf
20.5% Alaskan Malamute
18.1% Siberian Husky
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Genetic Stats

Wolfiness: 24.5 % HIGH Learn More
Predicted Adult Weight: 85 lbs Learn More
Genetic Age: 25 human years Learn More

DNA Breed Origins

What’s this?
Breed colors:
German Shepherd Dog
Gray Wolf
Alaskan Malamute
Siberian Husky

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Health

Traits

Maternal Haplotype

Paternal Haplotype

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Summary

0
AT RISK
0
CARRIER
169
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Orion Black Benoit has two normal alleles at ALT.

Not At Risk

Good news! Orion Black Benoit did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Orion Black Benoit does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Orion Black Benoit’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Orion Black Benoit is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Orion Black Benoit tested clear for 12 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Orion Black Benoit.

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Alaskan Malamutes, but not Orion Black Benoit.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Orion Black Benoit.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Orion Black Benoit.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Orion Black Benoit.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Orion Black Benoit.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Orion Black Benoit.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Orion Black Benoit.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Orion Black Benoit.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Orion Black Benoit.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in German Shepherd Dogs, Gray Wolfs, Alaskan Malamutes, Siberian Huskys, but not Orion Black Benoit.

Polyneuropathy, NDRG1 Malamute Variant
(NDRG1 Exon 4)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfution. Peripheral nerves relay messages between the brain and spinal cord to the rest …

Seen in Alaskan Malamutes, but not Orion Black Benoit.

Other Conditions: Clear of 157

Orion Black Benoit is clear of 157 other genetic diseases that Embark tests for.

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Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Ee
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
awat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red, Dudley)
BB

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
TT
Hairlessness (FOXI3)
LINKAGE
N/N
Oculocutaneous Albinism Type 2 - OCA2, Doberman Z Factor Albinism (SLC45A2)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Health

Maternal Haplotype

Paternal Haplotype

Through Orion Black Benoit’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18/19/20/21/27/36/94/109/361

Map

A1b

Orion Black Benoit’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18/19/20/21/27/36/94/109/361

Orion Black Benoit’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in over 25 countries across the world. We have detected this haplotype in lots of breeds, and it occurs most commonly in German Shepherd Dogs, Maltese, English Springer Spaniels, and English Setters.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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Health

Traits

Paternal Haplotype

Through Orion Black Benoit’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C

Haplotype

H5a

Map

C

Orion Black Benoit’s Haplogroup

C is a relatively rare paternal lineage. The dog populations which bear C are a disparate bunch. The Akita and Shiba Inu are Japanese breeds, the former of which seems to have roots in the Jomon population of hunter-gatherers which were present in the islands of Japan before the ancestors of the modern Japanese arrived. The New Guinea Singing Dog, Samoyed, and Alaska Malamute are all disparate breeds that also represent the C lineage. One village dog from Peru also bore this lineage. This wide distribution and diversity suggest C is not a recently expanded lineage. It likely represents a canid lineage which diversified sometime around the Last Glacial Maximum, when the dogs of Siberia and Oceania split off and went their separate ways.

H5a

Orion Black Benoit’s Haplotype

Part of the C haplogroup, this haplotype occurs most commonly in Akitas and Alaskan Malamutes.

Some other Embark dogs with this haplotype:

The Shiba Inu descends from this relativey rare haplogroup.

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Health

Traits

Maternal Haplotype