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Oliver

Beagle

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“Adopted from Beagle Rescue of Southern Maryland. We are not sure of his past he is very leery of humans, over the last couple of months he has been able to trust us more, he is extremely comfortable being around our two dogs that help him feel safe and secure.”

Place of Birth

Williamston, North Carolina, USA

Current Location

Odenton, Maryland, USA

From

Williamston Veterinary Hospital, US-17 BUS, Williamston, NC, U.S.

This dog has been viewed and been given 1 wag

Registration

Microchip: 991001003933858

Genetic Breed Result

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Genetic Stats

Wolfiness

0 % LOW

Predicted Adult Weight

30 lbs

Genetic Age
38 human years

Based on the date of birth provided

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Oliver’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Oliver is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Oliver inherited one copy of the variant we tested

How to interpret this result

Oliver has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Progressive Retinal Atrophy, crd4/cord1

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Oliver inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Oliver inherited one copy of the variant we tested

Why is this important to your vet?

Oliver has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Oliver has this genotype, as ALT is often used as an indicator of liver health and Oliver is likely to have a lower than average resting ALT activity. As such, an increase in Oliver’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency

Identified in Beagles

Pyruvate Kinase Deficiency

Identified in Beagles

Primary Open Angle Glaucoma

Identified in Beagles

Congenital Stationary Night Blindness

Identified in Beagles

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Dark brown pigment
Cocoa
No impact on fur and skin color
Red Pigment Intensity LINKAGE
I (Intensity) Loci
Any light fur likely yellow or tan
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Black/Brown and tan coat color pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
Saddle Tan
Likely saddle tan patterned
White Spotting
S (White Spotting) Locus
Likely to have large white areas in coat
Roan LINKAGE
R (Roan) Locus
Likely no impact on coat pattern
Merle
M (Merle) Locus
Unlikely to have merle pattern
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Intermediate
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Oliver’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B84

Map

B1

Oliver’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B84

Oliver’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most frequently in Golden Retrievers, Beagles, and Staffordshire Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Oliver’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.5

Map

A1a

Oliver’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.5

Oliver’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most commonly in Beagles.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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