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Obadiah

Doberman Pinscher

“We adopted Obadiah on 3/1/19 from a local shelter. We think he was 8-10 yrs old. He has definitely had a rough life. He had Pressure sores, scars all over his body, teeth are terrible filed all the way down to the nub’s some also broken, has been shot with a BB gun & has 2 Pellets still inside of him. He was diagnose with DCM(11/14/21), Spondylosis deformans, & Lumbar spinal stenosis(6/19/23) Obie we to be with the lord(7/27/23). We Miss U”

Instagram tag
@blessed_dobies

Current Location

Bakersfield, California, USA

From

Bakersfield, CA, USA

This dog has been viewed and been given 1 wag

Genetic Breed Result

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Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

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Changes to this dog’s profile
  • On 12/29/2021 changed name from "Obie" to "Obadiah"
Here’s what Obadiah’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Obadiah’s breed mix.

Breed Reveal Video

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Health Summary

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Obadiah is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Obadiah inherited one copy of the variant we tested

How to interpret this result

Obadiah has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Unilateral Deafness and Vestibular Syndrome

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Obadiah inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Obadiah’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Obadiah is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Unilateral Deafness and Vestibular Syndrome?

Hearing loss can be categorized into three groups: age-related, congenital (hearing loss present at birth), and early-onset (neonatally or during puppy or early adulthood). Causes of hearing loss are diverse, with a complex interaction of genetic and environmental components correlated with specific genes. This disease affects the hearing and balance mechanisms of the inner ear.

ALT Activity

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Obadiah inherited one copy of the variant we tested

Why is this important to your vet?

Obadiah has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Obadiah has this genotype, as ALT is often used as an indicator of liver health and Obadiah is likely to have a lower than average resting ALT activity. As such, an increase in Obadiah’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS

Identified in Doberman Pinschers

Narcolepsy

Identified in Doberman Pinschers

Dilated Cardiomyopathy, DCM1

Identified in Doberman Pinschers

Dilated Cardiomyopathy, DCM2

Identified in Doberman Pinschers

Ehlers Danlos

Identified in Doberman Pinschers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

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Through Obadiah’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B45

Map

B1

Obadiah’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B45

Obadiah’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, Doberman Pinschers, Cocker Spaniels, and village dogs in Costa Rica.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Obadiah’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.13

Map

A1b

Obadiah’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.13

Obadiah’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in Doberman Pinschers.

Great Danes and Pomeranians have this in common!

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