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“Chloé”
Nobelle

Stabyhoun

No bio has been provided yet

Place of Birth

Farum, Danmark

Current Location

Farum, Danmark

From

Hestetangsvej, Farum, Danmark

This dog has been viewed and been given 4 wags

Registration

N/A : DK00952/2017

Genetic Breed Result

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Stabyhoun

Renowned for its peaceful disposition, the Stabyhoun is a soft-mouthed retriever, a fine pointer, excellent tracker, and a good watchdog.

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Health Summary

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Chloé is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Chloé inherited one copy of the variant we tested

How to interpret this result

Chloé has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Degenerative Myelopathy, DM

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Chloé inherited both copies of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Chloé will develop Degenerative Myelopathy, DM.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Chloé's breed have been studied to know whether or not this variant will increase Chloé's risk of developing this disease.

Impact on Breeding

Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Degenerative Myelopathy, DM in your breeding program and related dogs.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

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Performance

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Through Chloé’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A16/17/99/100

Map

A1a

Nobelle’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A16/17/99/100

Nobelle’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Newfoundlands, German Shepherd Dogs, and Golden Retrievers.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Chloé inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Chloé is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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