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Neville

Australian Shepherd Group

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“Neville has an amazing temperament, very friendly personality, laid back, low to medium energy, great off switch, very smart, and always wants to please. He loves all people and is great with all dogs and cats. He loves playing with toys, fetching, and swimming. He's obsessed with water, swimming, and retrieving. Toys are his favorite and always has one in his mouth. He's super affectionate and cuddly, doesn't have an aggressive bone in his body. Very goofy and silly.”

Instagram tag
@darriontregre

Place of Birth

Upper Sandusky, OH, USA

Current Location

Franklin, New Hampshire, USA

From

Upper Sandusky, OH, USA

This dog has been viewed and been given 105 wags

Registration

American Stock Dog Registry (ASDR):

Genetic Breed Result

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Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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Genetic Stats

Wolfiness

1.5 % HIGH

Predicted Adult Weight

60 lbs

Genetic Age
29 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Australian Shepherd

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Health Summary

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Neville inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Neville inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Neville is unlikely to develop this condition due to the variant. This result may be important if you decide to breed this dog - we recommend genetic testing potential mates for this condition.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Neville inherited one copy of the variant we tested

Why is this important to your vet?

Neville has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Neville has this genotype, as ALT is often used as an indicator of liver health and Neville is likely to have a lower than average resting ALT activity. As such, an increase in Neville’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Shepherds and Australian Shepherds

Progressive Retinal Atrophy, prcd

Identified in Australian Shepherds and Australian Shepherds

Collie Eye Anomaly

Identified in Australian Shepherds and Australian Shepherds

Canine Multifocal Retinopathy, cmr1

Identified in Australian Shepherds and Australian Shepherds

Hereditary Cataracts

Identified in Australian Shepherds and Australian Shepherds

Urate Kidney & Bladder Stones

Identified in Australian Shepherds and Australian Shepherds

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Australian Shepherds and Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Shepherds and Australian Shepherds

Craniomandibular Osteopathy, CMO

Identified in Australian Shepherds and Australian Shepherds

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Neville’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A393

Map

A1a

Neville’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A393

Neville’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Yorkshire Terriers, Russel-type Terriers, and Tibetan Terriers.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through Neville’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.46

Map

A1a

Neville’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.46

Neville’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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