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Murphy

Mixed Ancestry

““Three families returned him to the shelter in his first year of life. They said he was tearing up their yard and trying to escape because they left him alone all day. Duhhhhh!” He's actually the best dog ever and I'm so glad the other people didn't like him.”

Current Location

San Mateo, California, USA

From

Amador County, CA, USA

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Genetic Breed Result

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Catahoula Leopard Dog

The Catahoula Leopard Dog is an American working breed with origins in Louisiana. These guys come in a patchwork of colors and patterns, giving them their trademark look. They are primarily a working dog, but can make good companions with intensive socialization from an early age.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Dogs Like Murphy

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Discover dogs who share a similar breed mix to Murphy. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
American Pit Bull Terrier
Catahoula Leopard Dog
Rottweiler

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Here’s what Murphy’s family tree may have looked like.
Murphy
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS American Pit Bull Terrier mix Catahoula Leopard Dog mix American Pit Bull Terrier Rottweiler mix Catahoula Leopard Dog American Pit Bull Terrier / Catahoula Leopard Dog mix American Pit Bull Terrier American Pit Bull Terrier Rottweiler Rottweiler mix Catahoula Leopard Dog Catahoula Leopard Dog American Pit Bull Terrier Catahoula Leopard Dog mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Murphy’s breed mix.
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Health Summary

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Murphy has one variant that you should let your vet know about.

ALT Activity

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Murphy inherited one copy of the variant we tested

Why is this important to your vet?

Murphy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Murphy has this genotype, as ALT is often used as an indicator of liver health and Murphy is likely to have a lower than average resting ALT activity. As such, an increase in Murphy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd2

Identified in American Pit Bull Terriers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers and Catahoula Leopard Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Murphy’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18/19/20/21/27/36/94/109

Map

A1b

Murphy’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18/19/20/21/27/36/94/109

Murphy’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in over 25 countries across the world. We have detected this haplotype in lots of breeds, and it occurs most commonly in German Shepherd Dogs, Maltese, English Springer Spaniels, and English Setters.

A1b is the most common haplogroup found in German Shepherds.

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Through Murphy’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H10.1

Map

D

Murphy’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H10.1

Murphy’s Haplotype

Part of the D haplogroup, this widespread haplotype occurs frequently in Boxers, Chinese Shar-pei, Croatian Shepherds, and village dogs throughout the South Pacific and southeast Asia.

The D paternal lineage is common in Boxers.

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