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Murphy

Mixed Ancestry

“He is not like any dog I've encountered. He doesn't have interest in other dogs, seldom barks, has never reacted to people at the door. He's incredibly "zen." Yet he plays obsessively and intensely, and has since the moment we adopted him from the shelter. That has led to him being in fantastic shape at 15. He's showing some age-related, early CKD. His coat has not changed color.”

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Genetic Breed Result

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Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

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Bulldog

Originally a bull-baiting dog, bulldogs today are gentle and loving while still carrying the stocky frame of their forbearers.

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Dachshund

The Dachshund, meaning “badger dog” in German, is a lively breed with a friendly personality and a great sense of smell. Known for their long and low bodies, they are spirited hunters that excel in both above and below-ground work. They come in three different coat varieties (smooth, wirehaired or longhaired) and can be miniature or standard size.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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American Eskimo Dog

American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Dogs Like Murphy

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Discover dogs who share a similar breed mix to Murphy. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Chihuahua
Bulldog
Dachshund
Labrador Retriever
Golden Retriever
American Eskimo Dog
German Shepherd Dog

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Here’s what Murphy’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Murphy’s breed mix.
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Health Summary

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Murphy has one variant that you should let your vet know about.

ALT Activity

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Murphy inherited one copy of the variant we tested

Why is this important to your vet?

Murphy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Murphy has this genotype, as ALT is often used as an indicator of liver health and Murphy is likely to have a lower than average resting ALT activity. As such, an increase in Murphy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Thrombopathia

Identified in American Eskimo Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd

Identified in American Eskimo Dogs, Chihuahuas, and more

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers and Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Chihuahuas, Dachshunds, and more

Day Blindness

Identified in German Shepherd Dogs

Day Blindness

Identified in Labrador Retrievers

Canine Multifocal Retinopathy, cmr1

Identified in Bulldogs

Primary Lens Luxation

Identified in American Eskimo Dogs

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in Bulldogs, German Shepherd Dogs, and more

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A, MPS IIIA

Identified in Dachshunds

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis 1, NCL 1

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 2, NCL 2

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 7, NCL 7

Identified in Chihuahuas

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

Alexander Disease

Identified in Labrador Retrievers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Chihuahuas

Degenerative Myelopathy, DM

Identified in American Eskimo Dogs, German Shepherd Dogs, and more

Narcolepsy

Identified in Labrador Retrievers

Muscular Dystrophy

Identified in Golden Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Osteogenesis Imperfecta

Identified in Dachshunds

Osteogenesis Imperfecta

Identified in Golden Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Intervertebral Disc Disease (Type I)

Identified in Chihuahuas and Dachshunds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Murphy’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Murphy’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Murphy’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Shar Pei dogs think A1a is the coolest!

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Through Murphy’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.4

Map

A1b

Murphy’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.4

Murphy’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs in North America and Africa. As for breeds, it occurs most frequently in Miniature Pinscher, Great Dane, and Poodle.

Great Danes and Pomeranians have this in common!

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