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“O'Reilly”
MSB's S'more Breath of Topaz Lightning Huiterty

Cockapoo

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Current Location

Cañon City, Colorado, USA

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Registration

american cockapoo club: HHEAD21CP1785

Genetic Breed Result

MSB's S'more Breath of Topaz Lightning Huiterty

“O'Reilly”
MSB's S'more Breath of Topaz Lightning Huiterty

Cockapoo
48.3% Poodle (Standard)
33.0% Poodle (Small)
18.7% Cocker Spaniel

Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Start a conversation! Message this dog’s owner.

Genetic Stats

Predicted Adult Weight

48 lbs

Genetic Age
15 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Poodle (Standard)
Poodle (Small)
Cocker Spaniel

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Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

MSB's S'more Breath of Topaz Lightning Huiterty
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Poodle (Standard) mix Poodle (Small) mix Cocker Spaniel / Poodle (Standard) mix Poodle (Standard) Poodle (Standard) / Poodle (Small) mix Poodle (Small) Poodle (Small) mix Cocker Spaniel Poodle (Standard) Poodle (Standard) Poodle (Standard) Poodle (Standard) Poodle (Small)

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain O'Reilly’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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O'Reilly is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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O'Reilly inherited one copy of the variant we tested

How to interpret this result

O'Reilly has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Degenerative Myelopathy, DM

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O'Reilly inherited one copy of the variant we tested

What does this result mean?

This result should not impact O'Reilly’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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O'Reilly inherited one copy of the variant we tested

Why is this important to your vet?

O'Reilly has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that O'Reilly has this genotype, as ALT is often used as an indicator of liver health and O'Reilly is likely to have a lower than average resting ALT activity. As such, an increase in O'Reilly’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles and Small Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Cocker Spaniels, Standard Poodles, and more

Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy, ARHN (COL4A4 Exon 3, Cocker Spaniel Variant)

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant)

Identified in Cocker Spaniels

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles and Small Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles and Small Poodles

Acral Mutilation Syndrome (GDNF-AS, Spaniel and Pointer Variant)

Identified in Cocker Spaniels

Exercise-Induced Collapse (DNM1)

Identified in Cocker Spaniels

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles and Small Poodles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (Ee)
K Locus (CBD103)
More likely to have a mostly solid black or brown coat (KBky)
Intensity Loci LINKAGE
No impact on coat pattern (Intermediate Red Pigmentation)
A Locus (ASIP)
Not expressed (ayat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (DD)
Cocoa (HPS3)
No co alleles, not expressed (NN)
B Locus (TYRP1)
Brown hair and skin (bb)
Saddle Tan (RALY)
Not expressed (NI)
S Locus (MITF)
Likely solid colored, but may have small amounts of white (Ssp)
M Locus (PMEL)
One merle allele, likely to appear merle or "phantom merle" (M*m)
R Locus (USH2A) LINKAGE
Likely no impact on coat pattern (rr)
H Locus (Harlequin)
No harlequin alleles (hh)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely furnished (mustache, beard, and/or eyebrows) (FF)
Coat Length (FGF5)
Likely long coat (TT)
Shedding (MC5R)
Likely light shedding (CT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely curly coat (TT)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Likely to have hind dew claws (CT)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Intermediate (NI)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Intermediate (TA)
Body Size (GHR - E191K)
Intermediate (GA)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)
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Through O'Reilly’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B84

Map

B1

MSB's S'more Breath of Topaz Lightning Huiterty’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B84

MSB's S'more Breath of Topaz Lightning Huiterty’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most frequently in Golden Retrievers, Beagles, and Staffordshire Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through O'Reilly’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.8/32/44

Map

A1a

MSB's S'more Breath of Topaz Lightning Huiterty’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.8/32/44

MSB's S'more Breath of Topaz Lightning Huiterty’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed-breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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