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Molly Mae

Mixed Breed

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“We adopted Molly Mae from a shelter when she was dropped off there after being hit by a car (which resulted in a hind leg amputation). One year later, this goober has made a full recovery and her playful, happy spirit has come to life. She absolutely loves cuddles, sniffs, and sleeping in. She hates the rain and prefers not to fall in a lake. She is the goofiest, sweetest, most affectionate and resilient light of our lives.”

Current Location

Seattle, Washington, USA

From

Seattle Animal Shelter, 15th Avenue West, Seattle, WA, USA

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Genetic Breed Result

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Australian Cattle Dog

A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.

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Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Genetic Stats

Wolfiness

1.2 % MEDIUM

Predicted Adult Weight

35 lbs

Genetic Age
40 human years

Based on the date of birth provided

Dogs Like Molly Mae

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Discover dogs who share a similar breed mix to Molly Mae. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
American Pit Bull Terrier
Australian Cattle Dog
Chow Chow
Supermutt

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Molly Mae
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS American Pit Bull Terrier mix American Pit Bull Terrier mix American Pit Bull Terrier Australian Cattle Dog mix American Pit Bull Terrier Australian Cattle Dog mix American Pit Bull Terrier American Pit Bull Terrier Australian Cattle Dog mix Mixed American Pit Bull Terrier American Pit Bull Terrier Australian Cattle Dog mix Mixed

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Molly Mae’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Molly Mae is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Urate Kidney & Bladder Stones

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Molly Mae inherited both copies of the variant we tested

How to interpret this result

Molly Mae has two copies of a variant in the SLC2A9 gene and is at risk for developing HUU. If you notice Molly Mae straining to urinate, producing urine tinged with blood, or not producing any urine at all, please seek veterinary care immediately; these are signs of urinary obstruction secondary to urolithiasis and could be life threatening.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

ALT Activity

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Molly Mae inherited one copy of the variant we tested

Why is this important to your vet?

Molly Mae has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Molly Mae has this genotype, as ALT is often used as an indicator of liver health and Molly Mae is likely to have a lower than average resting ALT activity. As such, an increase in Molly Mae’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Cattle Dogs

Progressive Retinal Atrophy, prcd

Identified in Australian Cattle Dogs

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Collie Eye Anomaly

Identified in Australian Cattle Dogs

Primary Lens Luxation

Identified in Australian Cattle Dogs

Cystinuria Type II-A

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Cattle Dogs

Late-Onset Neuronal Ceroid Lipofuscinosis, NCL 12

Identified in Australian Cattle Dogs

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Myotonia Congenita

Identified in Australian Cattle Dogs

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Dark brown pigment
Cocoa
No impact on fur and skin color
Red Pigment Intensity LINKAGE
I (Intensity) Loci
No impact on coat pattern
Brown or Black Pigment
B (Brown) Locus
Brown fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
No impact on coat pattern
White Spotting
S (White Spotting) Locus
Likely to have some white areas in coat
Roan LINKAGE
R (Roan) Locus
Likely no impact on coat pattern
Merle
M (Merle) Locus
Unlikely to have merle pattern
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Intermediate
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Intermediate
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Molly Mae’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A604

Map

A1d

Molly Mae’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A604

Molly Mae’s Haplotype

Part of the A1d haplogroup, the A604 haplotype occurs most commonly in Australian Shepherds. It's a rare find!

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Molly Mae inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Molly Mae is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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