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Ru

Dalmatian

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Current Location

Eagan, Minnesota, USA

From

Bemidji, MN, USA

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Genetic Breed Result

Dalmatian

Ru

embk.me/i/mizru

Dalmatian

Best known as the star of Disney’s 101 Dalmatians, this sleek and athletic dog breed has a history that goes back several hundred years. He started out as a coach dog but has also served in many other capacities, including hunter, firehouse dog, and circus performer. As charming in life as in film, he goes from gallant to goofy to gallant again in the blink of an eye, and loves to be a part of everything his family does.

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Genetic Stats

Wolfiness

0.9 % MEDIUM

Predicted Adult Weight

48 lbs

Genetic Age
22 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 10/17/2020 changed name from "Miz Ru" to "Ru"
  • On 7/15/2020 changed handle from "nasima" to "mizru"
  • On 6/17/2020 changed name from "Nasima" to "Miz Ru"

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Ru’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Ru is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Urate Kidney & Bladder Stones

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Ru inherited both copies of the variant we tested

How to interpret this result

Ru has two copies of a variant in the SLC2A9 gene and is at risk for developing HUU. If you notice Ru straining to urinate, producing urine tinged with blood, or not producing any urine at all, please seek veterinary care immediately; these are signs of urinary obstruction secondary to urolithiasis and could be life threatening.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

ALT Activity

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Ru inherited one copy of the variant we tested

Why is this important to your vet?

Ru has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ru has this genotype, as ALT is often used as an indicator of liver health and Ru is likely to have a lower than average resting ALT activity. As such, an increase in Ru’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Red Pigment Intensity LINKAGE
I (Intensity) Loci
No impact on coat pattern
Brown or Black Pigment
B (Brown) Locus
Brown fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
Saddle Tan
No impact on coat pattern
White Spotting
S (White Spotting) Locus
Likely to have large white areas in coat
Merle
M (Merle) Locus
Unlikely to have merle pattern
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Ru’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Ru’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Ru’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Ru inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ru is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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