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Mishka

Central Asian Shepherd Dog

“Imported from Vladivostok, Russia in 2018. UKC’s number one Central Asian Shepherd for 2019. Beloved family member living her best life in Port Dover, Ontario.”

Place of Birth

Vladivostok, Russia

Current Location

Port Dover, ON, Canada

From

Vladivostok, Russia

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Registration

United Kennel Club (UKC): P885-610

Genetic Breed Result

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Central Asian Shepherd Dog

The Central Asian Shepherd Dog is a large, powerful breed that originates from, well, Central Asia! They are an ancient breed that hails from modern day countries like Kazakstan, Afghanistan, and Tadzhikistan. They were bred over the course of thousands of years to be an excellent guardian of livestock—usually sheep—and a faithful companion to their owner. While the Central Asian Sheepdog’s bloodline can be traced over a thousand years, they weren’t commercially bred in kennels until the 20th century in the former USSR.

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Health Summary

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Mishka has one variant that you should let your vet know about.

ALT Activity

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Mishka inherited one copy of the variant we tested

Why is this important to your vet?

Mishka has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Mishka has this genotype, as ALT is often used as an indicator of liver health and Mishka is likely to have a lower than average resting ALT activity. As such, an increase in Mishka’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Dystrophic Epidermolysis Bullosa (COL7A1, Central Asian Shepherd Dog Variant)

Identified in Central Asian Shepherd Dogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Mishka’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C7/10

Map

C1

Mishka’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C7/10

Mishka’s Haplotype

Part of the C1 haplogroup, this haplotype occurs most commonly in Pekingese, Boston Terriers, and Rat Terriers.

The C1 maternal line is commonly found in Jackals.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Mishka inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Mishka is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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