What is Embark?

“Dodger”
Millstones Fame In The City Of Angels

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See what’s hidden in the pages of Dodger’s DNA story.

“Named after Dodger Stadium”

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Registration

AKC: SS04860702

Genetic Breed

Golden Retriever

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Genetic Stats

Wolfiness: 0.3 % LOW
Predicted Adult Weight: 74 lbs
Genetic Age: 7 human years

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Health

>
We have tested Dodger for over 160 genetic health conditions to alert his owner to potential issues before they strike.

Traits

>
Genes for coat color and type, body size and shape, and other characteristics.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about other dog breeds related to the breeds found in Dodger.

Maternal Haplotype

>
Through the DNA inherited from Dodger’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Dodger’s family has traveled.

Paternal Haplotype

>
The Y-Chromosome is only passed down from father to son. Dodger’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Dodger’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Dodger find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Summary

0
AT RISK
0
CARRIER
165
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Millstones Fame In The City Of Angels has two copies of a mutation associated with reduced ALT activity. Please inform your veterinarian that Millstones Fame In The City …

Not At Risk

Good news! Dodger did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Dodger does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Dodger’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Dodger is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Dodger tested clear for 9 genetic conditions that are common in his breed.
Condition List

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Neuronal Ceroid Lipofuscinosis
(CLN5 Exon 4 Variant 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Muscular Dystrophy
Muscular Dystrophy (DMD Golden Retriever Variant)
Muscular

Characterized by non-painful muscle weakness and wasting, early diagnosis and supportive treatment can slow the pace of this progressive muscle disease. All known mutatio…

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Dystrophic Epidermolysis Bullosa
(COL7A1)
Skin & Connective Tissues

This skin disorder gives affected dogs skin that stretches and tears easily; affected dogs must be monitored closely and treated promptly for any injuries. It arises from…

Ichthyosis
(PNPLA1)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin (“ichthys” is Greek for “fish”) that affected dogs display on their noses, paw pads, and …

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A1)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Other Conditions: Clear of 156

Dodger is clear of 156 other genetic diseases that Embark tests for.

Explore more

Swipe left and right to explore more results, or choose a category below

Traits

>
Genes for coat color and type, body size and shape, and other characteristics.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about other dog breeds related to the breeds found in Dodger.

Maternal Haplotype

>
Through the DNA inherited from Dodger’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Dodger’s family has traveled.

Paternal Haplotype

>
The Y-Chromosome is only passed down from father to son. Dodger’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

What’s your dog’s story?

Now that you have explored what’s behind Dodger find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask, Grizzle, Recessive Red)
ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
KBKB
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti, Sable)
ata
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute, Blue, Fawn)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown, Chocolate, Liver, Red)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Furnishings / Improper Coat (RSPO2)
II
Chromosome 13

Confers the distinguished moustache, beard, and eyebrows characteristic of breeds like the Schnauzer, Scottish Terrier, and Wire Haired Dachshund; only one copy of the dominant F allele is required for furnishings. The FI genotype is furnished but carries one allele for no furnishings, or improper coat. A dog with two I alleles has improper coat. The mutation is a 167-bp insertion which we measure indirectly using linked markers highly correlated with the insertion.

Citations: Cadieu et al 2010

Long Haircoat (FGF5)
TT
Chromosome 32

The FGF5 gene is known to affect hair length in many different species, including cats, dogs, mice, and humans! The "T" allele confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The ancestral "G" allele causes a shorter coat as seen in the Boxer or the American Staffordshire Terrier.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CC
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a wavy or curly coat; the ancestral "C" allele is associated with a straight coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Natural Bobtail (T)
CC
Chromosome 1

Whereas most dogs have two C alleles and a long tail, dogs with one G allele are likely to have a bobtail, which is an unusually short or absent tail. This mutation causes natural bobtail in many breeds including the Pembroke Welsh Corgi, the Australian Shepherd, and the Brittany Spaniel. Dogs with GG genotypes have not been observed, suggesting that the GG genotype results in embryonic lethality.

Please note that this mutation does not explain every natural bobtail! While certain lineages of Boston Terrier, English Bulldog, Rottweiler, Miniature Schnauzer, Cavalier King Charles Spaniel, and Parson Russell Terrier, and Dobermans are born with a natural bobtail, these breeds do not have this mutation. This suggests that other unknown genetic mutations can also lead to a natural bobtail. If your dog does not have a CG genotype but was born with a bobtail, please email us at howdy@embarkvet.com!

Citations: Haworth et al 2001 , Hytonen et al 2009

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

Body Size - IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

Body Size - IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

Body Size - STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Explore more

Swipe left and right to explore more results, or choose a category below

Health

>
We have tested Dodger for over 160 genetic health conditions to alert his owner to potential issues before they strike.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about other dog breeds related to the breeds found in Dodger.

Maternal Haplotype

>
Through the DNA inherited from Dodger’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Dodger’s family has traveled.

Paternal Haplotype

>
The Y-Chromosome is only passed down from father to son. Dodger’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

What’s your dog’s story?

Now that you have explored what’s behind Dodger find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Golden Retriever
4 related breeds
Golden Retriever
Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.
Related Breeds
Flat-Coated Retriever
Sibling breed
Labrador Retriever
Sibling breed
Chesapeake Bay Retriever
Cousin breed
Newfoundland
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Explore more

Swipe left and right to explore more results, or choose a category below

Health

>
We have tested Dodger for over 160 genetic health conditions to alert his owner to potential issues before they strike.

Traits

>
Genes for coat color and type, body size and shape, and other characteristics.

Maternal Haplotype

>
Through the DNA inherited from Dodger’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Dodger’s family has traveled.

Paternal Haplotype

>
The Y-Chromosome is only passed down from father to son. Dodger’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

What’s your dog’s story?

Now that you have explored what’s behind Dodger find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Through Dodger’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1b

Map

B1

Millstones Fame In The City Of Angels’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1b

Millstones Fame In The City Of Angels’s Haplotype

Part of the large B1 haplogroup, we see this haplotype in village dogs across the world, including those from Central America, the Middle East, South Asia, and the French Polynesian Islands. Among the 31 breed dogs we see it in, we see it in Poodles, Otterhounds, and Labrador Retrievers. It is also our most commonly-sampled Golden Retriever haplotype!

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Explore more

Swipe left and right to explore more results, or choose a category below

Health

>
We have tested Dodger for over 160 genetic health conditions to alert his owner to potential issues before they strike.

Traits

>
Genes for coat color and type, body size and shape, and other characteristics.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about other dog breeds related to the breeds found in Dodger.

Paternal Haplotype

>
The Y-Chromosome is only passed down from father to son. Dodger’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

What’s your dog’s story?

Now that you have explored what’s behind Dodger find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Through Dodger’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.20

Map

A1a

Millstones Fame In The City Of Angels’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.20

Millstones Fame In The City Of Angels’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in village dogs throughout the world (outside of Asia). It is quite common in breed dogs, occurring frequently in Golden Retrievers, Irish Wolfhounds, Scottish Terriers, Border Collies, and Mastiffs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

Explore more

Swipe left and right to explore more results, or choose a category below

Health

>
We have tested Dodger for over 160 genetic health conditions to alert his owner to potential issues before they strike.

Traits

>
Genes for coat color and type, body size and shape, and other characteristics.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about other dog breeds related to the breeds found in Dodger.

Maternal Haplotype

>
Through the DNA inherited from Dodger’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Dodger’s family has traveled.

What’s your dog’s story?

Now that you have explored what’s behind Dodger find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!