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Millie

Mixed Breed

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  • Photo of Millie, an Australian Cattle Dog, Great Pyrenees, Labrador Retriever, and Border Collie mix in St. Louis, Missouri, USA Photo of Millie, an Australian Cattle Dog, Great Pyrenees, Labrador Retriever, and Border Collie mix in St. Louis, Missouri, USA
    16 weeks

“She LOVES food! She loves to watch tv (her favorite show is Bluey, and she loves to see animals-real or cartoon, and nature documentaries.) She is very chatty (grumbles, gurgles/yodels, moans, barks, howls.) She is quite athletic and high energy. She loves to play fetch, learns new cues quickly, and chases a sweeping broom or a hand cleaning a glass patio door! She is shy with new people and dogs, but we’re working on it and making progress! Adopted on New Year’s Eve 2021 at around 9.5 wks old.”

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@Millie_thenewyearsdog

Current Location

St. Louis, Missouri, USA

From

Animal Protective Association/APA Adoption Center, South Hanley Road, Brentwood, MO, USA

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Genetic Breed Result

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Australian Cattle Dog

A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.

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Great Pyrenees

The Great Pyrenees is an exceptionally loving dog whose primary function is to protect sheep, goats, livestock, people, children, grass, flowers, the moon, lawn furniture, etc., from any real or imaginary predators that may intrude on your personal space. They have a strong build and an amazing thick white coat that exudes elegance and majesty. They make a great family dog because of their intelligence and steady temperament.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Border Collie

Border Collies are highly energetic and work-oriented herding dogs, whose stamina is matched by their intelligence and alertness. While they excel at the herding they were bred for, many Border Collies also enjoy flyball, obedience, and other canine sports. As long as they have a job to do and are physically and mentally stimulated, Border Collies can make excellent companions for the right owners.

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Dogs Like Millie

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Discover dogs who share a similar breed mix to Millie. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Australian Cattle Dog
Great Pyrenees
Labrador Retriever
Border Collie
Beagle
Golden Retriever

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Millie
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Australian Cattle Dog / Labrador Retriever mix Great Pyrenees / Beagle mix Australian Cattle Dog / Border Collie mix Great Pyrenees / Labrador Retriever mix Australian Cattle Dog Labrador Retriever mix Great Pyrenees Beagle mix Australian Cattle Dog Border Collie mix Great Pyrenees Labrador Retriever

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Millie’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Millie inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Collie Eye Anomaly

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Millie inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Collie Eye Anomaly?

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia. The choroid anchors the retina to the underlying structures and supplies it with oxygen and nourishment. CEA is a developmental disease of the choroid.

Exercise-Induced Collapse, EIC

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Millie inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Exercise-Induced Collapse, EIC?

EIC has been linked to a mutation in the DNM1 gene, which codes for the protein dynamin. In the neuron, dynamin trucks neurotransmitter-filled vesicles from the cell body, where they are generated, to the dendrites. It is hypothesized in dogs affected with EIC, the mutation in DNM1 disrupts efficient neurotransmitter release, leading to a cessation in signalling and EIC.

ALT Activity

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Millie inherited one copy of the variant we tested

Why is this important to your vet?

Millie has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Millie has this genotype, as ALT is often used as an indicator of liver health and Millie is likely to have a lower than average resting ALT activity. As such, an increase in Millie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Cattle Dogs and Border Collies

Factor VII Deficiency

Identified in Beagles

Canine Elliptocytosis

Identified in Labrador Retrievers

Glanzmann's Thrombasthenia Type I

Identified in Great Pyrenees

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Beagles

Trapped Neutrophil Syndrome, TNS

Identified in Border Collies

Progressive Retinal Atrophy, prcd

Identified in Australian Cattle Dogs, Golden Retrievers, and more

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers and Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles and Labrador Retrievers

Day Blindness

Identified in Labrador Retrievers

Canine Multifocal Retinopathy, cmr1

Identified in Great Pyrenees

Primary Open Angle Glaucoma

Identified in Beagles

Goniodysgenesis and Glaucoma, Pectinate Ligament Dysplasia, PLD

Identified in Border Collies

Primary Lens Luxation

Identified in Australian Cattle Dogs and Border Collies

Congenital Stationary Night Blindness

Identified in Beagles

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Cystinuria Type II-A

Identified in Australian Cattle Dogs

Urate Kidney & Bladder Stones

Identified in Labrador Retrievers

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Australian Cattle Dogs and Border Collies

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

Late-Onset Neuronal Ceroid Lipofuscinosis, NCL 12

Identified in Australian Cattle Dogs

Alexander Disease

Identified in Labrador Retrievers

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in Golden Retrievers and Great Pyrenees

Narcolepsy

Identified in Labrador Retrievers

Sensory Neuropathy

Identified in Border Collies

Muscular Dystrophy

Identified in Golden Retrievers

Ullrich-like Congenital Muscular Dystrophy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Myotonia Congenita

Identified in Australian Cattle Dogs and Border Collies

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Border Collies

Cobalamin Malabsorption

Identified in Beagles

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Golden Retrievers

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Osteogenesis Imperfecta

Identified in Golden Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Raine Syndrome

Identified in Border Collies

Intervertebral Disc Disease (Type I)

Identified in Beagles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Millie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A394

Map

A1a

Millie’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A394

Millie’s Haplotype

Part of the A1a haplogroup, the A394 haplotype occurs most commonly in Labrador Retrievers. It's a rare find!

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Millie inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Millie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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