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Maxomagic’s Revolutionary War CGC TKN

Central Asian Shepherd Dog

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“Registered UKC and AKC FSS. Completed STAR Puppy, Canine Good Citizen, Trick Dog Novice. Number 3 Central Asian Shepherd UKC 2019”

Place of Birth

Middletown, NY, USA

Current Location

Pennsylvania, USA

From

MaxoMagic Central Asian Shepherds, U.S. 6, Middletown, Orange County, NY, USA

This dog has been viewed and been given 4 wags

Registration

United Kennel Club (UKC): P890-644

Genetic Breed Result

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Central Asian Shepherd Dog

The Central Asian Shepherd Dog is a large, powerful breed that originates from, well, Central Asia! They are an ancient breed that hails from modern day countries like Kazakstan, Afghanistan, and Tadzhikistan. They were bred over the course of thousands of years to be an excellent guardian of livestock—usually sheep—and a faithful companion to their owner. While the Central Asian Sheepdog’s bloodline can be traced over a thousand years, they weren’t commercially bred in kennels until the 20th century in the former USSR.

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Health Summary

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Maxomagic’s Revolutionary War has one variant that you should let your vet know about.

ALT Activity

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Maxomagic’s Revolutionary War inherited one copy of the variant we tested

Why is this important to your vet?

Maxomagic’s Revolutionary War has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Maxomagic’s Revolutionary War has this genotype, as ALT is often used as an indicator of liver health and Maxomagic’s Revolutionary War is likely to have a lower than average resting ALT activity. As such, an increase in Maxomagic’s Revolutionary War’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Dystrophic Epidermolysis Bullosa (COL7A1, Central Asian Shepherd Dog Variant)

Identified in Central Asian Shepherd Dogs

Additional Genetic Conditions

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Through Maxomagic’s Revolutionary War’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A381

Map

A1a

Maxomagic’s Revolutionary War’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A381

Maxomagic’s Revolutionary War’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Doberman Pinschers, and Dachshunds.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Maxomagic’s Revolutionary War inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Maxomagic’s Revolutionary War is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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