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Mandy

Mixed Ancestry

No bio has been provided yet

Current Location

St Paul, Indiana, USA

From

Bloomington, Indiana, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Treeing Walker Coonhound

The Treeing Walker Coonhound is phenomenal hunter and working dog. These hardy hounds were built with unmatched speed and stamina in their respective category. This American breed is mainly used today as a working/hunting dog, but can still make a wonderful companion.

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Bluetick Coonhound

Bluetick Coonhounds are an American breed of hound that originated in the Southern United States, which is a pretty common story for American breeds, particularly hounds. While they can make good house dogs, Bluetick Coonhounds are still mostly hunting dogs.

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Yorkshire Terrier

Petite but proud, the Yorkshire terrier is a popular toy breed with a silky, low-shedding coat.

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Pug

The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. Pugs are known for being sociable and gentle companion dogs.

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Dogs Like Mandy

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Discover dogs who share a similar breed mix to Mandy. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Beagle
Pomeranian
Treeing Walker Coonhound
Bluetick Coonhound
Yorkshire Terrier
Pug
Supermutt

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Here’s what Mandy’s family tree may have looked like.
Mandy
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Beagle / Treeing Walker Coonhound mix Pomeranian / Yorkshire Terrier mix Beagle / Pomeranian mix Bluetick Coonhound / Treeing Walker Coonhound mix Beagle Treeing Walker Coonhound mix Pomeranian Yorkshire Terrier mix Beagle Pomeranian mix Bluetick Coonhound mix Treeing Walker Coonhound mix
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Mandy’s breed mix.

Breed Reveal Video

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Health Summary

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Mandy is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Mandy inherited one copy of the variant we tested

How to interpret this result

Mandy has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Mandy inherited both copies of the variant we tested

Why is this important to your vet?

Mandy has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Mandy's ALT activity above their current, healthy, ALT activity. As an increase above Mandy’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency

Identified in Beagles

May-Hegglin Anomaly

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Beagles

Methemoglobinemia

Identified in Pomeranians

Progressive Retinal Atrophy, rcd3

Identified in Pomeranians

Progressive Retinal Atrophy, prcd

Identified in Yorkshire Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Primary Open Angle Glaucoma

Identified in Beagles

Primary Lens Luxation

Identified in Yorkshire Terriers

Urate Kidney & Bladder Stones

Identified in Pomeranians

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in Pugs

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Oculocutaneous Albinism, OCA

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets

Identified in Pomeranians

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Mandy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C35

Map

C1

Mandy’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C35

Mandy’s Haplotype

Part of the C1 haplogroup, the C35 haplotype occurs most commonly in Yorkshire Terriers. It's a rare find!

The C1 maternal line is commonly found in Jackals.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Mandy inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Mandy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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