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Major

Mixed Breed

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Current Location

Fairfax, Virginia, USA

From

Lovingston, VA, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from this distant ancestor:

Keeshond

The Keeshond is one of the friendliest dogs out there. They appear to have a permenant smile on their face. They were originally bred as watchdogs in Holland, but now serve a lovable companions in the home.

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Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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American Eskimo Dog

American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Collie

Collies are attractive herding dogs, boasting a beautiful coat while being highly intelligent. They also make for extremely loyal and sweet family pets.

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Genetic Stats

Wolfiness

1.7 % HIGH

Predicted Adult Weight

30 lbs

Genetic Age
78 human years

Based on the date of birth provided

Dogs Like Major

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Discover dogs who share a similar breed mix to Major. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Keeshond
Chow Chow
Beagle
Pomeranian
American Eskimo Dog
German Shepherd Dog
Collie
Supermutt

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Major
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Beagle mix Pomeranian / Keeshond mix Chow Chow / German Shepherd Dog mix American Eskimo Dog / Collie mix Beagle Mixed Pomeranian Keeshond Chow Chow German Shepherd Dog mix American Eskimo Dog Collie mix

Our algorithms predict this is the most likely family tree to explain Major’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Major is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Major inherited one copy of the variant we tested

How to interpret this result

Major has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Progressive Retinal Atrophy, crd4/cord1

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Major inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Collies and German Shepherd Dogs

Factor VII Deficiency

Identified in Beagles

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Thrombopathia

Identified in American Eskimo Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, rcd3

Identified in Pomeranians

Progressive Retinal Atrophy, prcd

Identified in American Eskimo Dogs

Collie Eye Anomaly

Identified in Collies

Day Blindness

Identified in German Shepherd Dogs

Primary Open Angle Glaucoma

Identified in Beagles

Primary Lens Luxation

Identified in American Eskimo Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs and Pomeranians

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in American Eskimo Dogs and German Shepherd Dogs

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Hereditary Vitamin D-Resistant Rickets

Identified in Pomeranians

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Clinical Tools

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Major’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A234

Map

A1e

Major’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A234

Major’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs in village dogs in South America, South Asia, and into the South Pacific. Among breeds, we see it in highest frequency among Vizslas, Boxers, and Yorkshire Terriers.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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Through Major’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.2

Map

A2b

Major’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.2

Major’s Haplotype

Part of the A2b haplogroup, this haplotype has been found in Chinese Shar-pei and village dogs in Papua New Guinea.

Some other Embark dogs with this haplotype:

A2b is found in the Daschund breed.

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