Maddy inherited one copy of the variant we tested
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Changes to this dog’s profile
- On 12/22/2019 changed name from "Maddy" to "Roseheaven’s Madelaine"
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Maddy has one variant that you should let your vet know about.
Why is this important to your vet?
Maddy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Maddy has this genotype, as ALT is often used as an indicator of liver health and Maddy is likely to have a lower than average resting ALT activity. As such, an increase in Maddy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
GM2 Gangliosidosis (HEXA, Japanese Chin Variant)
Identified in Japanese Chins