Lusa

Beagle

“Lusa is a lemon and white beagle puppy from Patch kennel lines. She is spunky and smart. WEIGHT 6 weeks - 3 lbs 9 weeks - 6 lbs 12 weeks - 10 lbs 15 weeks - 15 lbs 20 weeks - 21 lbs”

Place of Birth
Kentucky, USA
Current Location
Illinois, USA
From
Kentucky, USA

This dog has been viewed 392 times and been given 7 wags

Genetic Breed Result

Learn how it’s done

Beagle

100.0% Beagle
Beagle Beagle
The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.
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Genetic Stats


Wolfiness

1.5 % HIGH Learn More

Predicted Adult Weight
Genetic Age
11 human years Learn More
Based on the date of birth provided

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Explore by tapping the parents and grandparents.

Breed Reveal Video

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Our algorithms predict this is the most likely family tree to explain Lusa’s breed mix, but this family tree may not be the only possible one.

Health Summary

Lusa is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

Lusa inherited both copies of the variant we tested

How to interpret this result

Lusa has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Hypocatalasia, Acatalasemia

Lusa inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them. This result is also important if you decide to breed this dog - to produce the healthiest puppies we recommend genetic testing any potential mates for this condition.

What is Hypocatalasia, Acatalasemia?

Catalase is important in fighting reactive oxygen species, which can cause cellular damage. Fortunately, many enzymes can break down reactive oxygen species; as such acatalasemia is usually a benign disease: however, some acatalasemic dogs suffer from what is known as Takahara’s disease, where patients have progressive mouth ulcers.


ALT Activity

Lusa inherited one copy of the variant we tested

Why is this important to your vet?

Lusa has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Lusa has this genotype, as ALT is often used as an indicator of liver health and Lusa is likely to have a lower than average resting ALT activity. As such, an increase in Lusa’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Factor VII Deficiency

Identified in Beagles

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy - crd4/cord1

Identified in Beagles

Glaucoma

Identified in Beagles

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Light colored fur (cream to red)
Brown or Black Pigment
B (Brown) Locus
Likely brown colored nose/feet
Color Dilution
D (Dilute) Locus
Dark (non-dilute) skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
No impact on coat color
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
No dark fur anywhere
Saddle Tan
No impact on coat pattern
White Spotting
S (White Spotting) Locus
Likely to have large white areas in coat
Merle
M (Merle) Locus
No impact on coat color
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation

Through Lusa’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A2a

Map

A1e

Lusa’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A2a

Lusa’s Haplotype

Part of the large A1e haplogroup, we see this haplotype in village dogs up and down the Americas as well as French Polynesia. Among the breed dogs we have detected it in, we see it most frequently in English Springer Spaniels, Papillons, and Collies.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Lusa inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Lusa is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.