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Luna

Great Dane

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Place of Birth

Ottawa, ON, Canada

Current Location

Ottawa, Ontario, Canada

From

Ottawa, ON, Canada

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Genetic Breed Result

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Great Dane

Great Danes are large lovable dogs that need exercise and space. Many Great Danes are "leaners"-- they lean against their people to be closer to them, seemingly oblivious to their size!

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Genetic Stats

Predicted Adult Weight

98 lbs

Genetic Age
21 human years

Based on the date of birth provided

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Luna’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Luna has one variant that you should let your vet know about.

ALT Activity

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Luna inherited both copies of the variant we tested

Why is this important to your vet?

Luna has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Luna's ALT activity above their current, healthy, ALT activity. As an increase above Luna’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Inherited Myopathy of Great Danes (BIN1)

Identified in Great Danes

Ichthyosis (SLC27A4, Great Dane Variant)

Identified in Great Danes

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Luna’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C17

Map

C2

Luna’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C17

Luna’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most commonly in village dogs from Nepal.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Luna inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Luna is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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