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Luna

Doberman Pinscher

“Luna came from a BYB in Washington. She is very accomplished as she has earned 17 different titles. She is a registered therapy dog, has achieved 9 different trick dog titles including trick dog champion, and has titled in rally and agility as well. Her litter was born on 12/16/16 in Washington.”

Instagram tag
@Luna_eclipse_dobermans

Place of Birth
Pe Ell, WA, USA
Current Location
Dayton, Nevada, USA
From
Pe Ell, WA, USA

This dog has been viewed 351 times and been given 43 wags

Genetic Breed Result

Learn how it’s done

Doberman Pinscher

100.0% Doberman Pinscher
Doberman Pinscher Doberman Pinscher
Doberman Pinschers are a strong and athletic breed that are built to guard and protect.
Learn More
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Genetic Stats


Wolfiness

0.9 % MEDIUM Learn More

Predicted Adult Weight
Genetic Age
35 human years Learn More
Based on the date of birth provided

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Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Luna’s breed mix, but this family tree may not be the only possible one.

Health Summary

Luna is at increased risk for two genetic health conditions.

And inherited three variants that you should learn more about.

Dilated Cardiomyopathy, DCM1

Luna inherited one copy of the variant we tested

How to interpret this result

Luna has one copy of a variant in the PDK4 gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM1, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Luna shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Luna.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.


Dilated Cardiomyopathy, DCM2

Luna inherited both copies of the variant we tested

How to interpret this result

Luna has two copies of a variant in TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Luna shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Luna. We measure this result using a linkage test.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Von Willebrand Disease Type I

Luna inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Von Willebrand Disease Type I?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.


Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS

Luna inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS?

This disease affects the hearing and balance mechanisms of the inner ear.


ALT Activity

Luna inherited one copy of the variant we tested

Why is this important to your vet?

Luna has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Luna has this genotype, as ALT is often used as an indicator of liver health and Luna is likely to have a lower than average resting ALT activity. As such, an increase in Luna’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions


Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Brown fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Black/Brown and tan coat color pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
Likely saddle tan patterned
Merle
M (Merle) Locus
Unlikely to have merle pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation

Through Luna’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A408

Map

A1b

Luna’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A408

Luna’s Haplotype

Part of the A1b haplogroup, the A408 haplotype occurs most commonly in Doberman Pinschers. It's a rare find!

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Luna inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Luna is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.