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“Chaser”
Lucy&Titan -Black-Zeen Nightshade (Chaser)

Poodle

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Current Location

Caldwell, ID, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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DNA Breed Origins

Breed colors:
Poodle (Small)
Poodle (Standard)

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Here’s what Chaser’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Chaser’s breed mix.

Breed Reveal Video

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Health Summary

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Chaser is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Chaser inherited one copy of the variant we tested

How to interpret this result

Chaser has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Chaser inherited one copy of the variant we tested

Why is this important to your vet?

Chaser has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Chaser has this genotype, as ALT is often used as an indicator of liver health and Chaser is likely to have a lower than average resting ALT activity. As such, an increase in Chaser’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles, Small Poodles, and more

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Standard Poodles, Small Poodles, and more

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles, Small Poodles, and more

Degenerative Myelopathy, DM (SOD1A)

Identified in Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles, Small Poodles, and more

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles, Small Poodles, and more

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Chaser’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Lucy&Titan -Black-Zeen Nightshade (Chaser)’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Lucy&Titan -Black-Zeen Nightshade (Chaser)’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

A1b is the most common haplogroup found in German Shepherds.

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Through Chaser’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.7

Map

A1b

Lucy&Titan -Black-Zeen Nightshade (Chaser)’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.7

Lucy&Titan -Black-Zeen Nightshade (Chaser)’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs from Lebanon and Indonesia. Among breeds, it is also found in Miniature Schnauzer and Toy Poodle.

Great Danes and Pomeranians have this in common!

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