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Lucy

Olde English Bulldogge

“Lucy is a smart girl that was born in Hawaii and moved to CO in 2019. She had her first and only litter in 2019 with 11 puppies. 5 males and 6 females. All are very healthy! If you want to learn more about Lucy the website is www.coloradooldeenglishbulldogge.com”

Instagram tag
@CO_OLDE_BULLDOGGES

Place of Birth
Big Island, Hawaii, USA
Current Location
Colorado Springs, Colorado, USA
From
Big Island, Hawaii, USA

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Genetic Breed Result

Learn how it’s done

Olde English Bulldogge

100.0% Olde English Bulldogge
Olde English Bulldogge Olde English Bulldogge
Though its name is deceiving, the Olde English Bulldogge is a fairly young breed, developed by American breeders in the 1970s with the aim to recreate the original working bulldog from 19th century England.
Learn More
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Genetic Stats


Predicted Adult Weight
Genetic Age
31 human years Learn More
Based on the date of birth provided

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Explore by tapping the parents and grandparents.

Breed Reveal Video

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Our algorithms predict this is the most likely family tree to explain Lucy’s breed mix, but this family tree may not be the only possible one.

Health Summary

Lucy inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

Lucy inherited one copy of the variant we tested

What does this result mean?

This result should not impact Lucy’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

This result should be taken into account as part of your breeding program. Lucy will pass this variant to ~50% of her offspring.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.


ALT Activity

Lucy inherited one copy of the variant we tested

Why is this important to your vet?

Lucy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Lucy has this genotype, as ALT is often used as an indicator of liver health and Lucy is likely to have a lower than average resting ALT activity. As such, an increase in Lucy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Progressive Retinal Atrophy, crd1 (PDE6B)

Identified in Olde English Bulldogges

Canine Multifocal Retinopathy (BEST1 Exon 2)

Identified in Olde English Bulldogges

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Olde English Bulldogges

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia, NCL4A (ARSG Exon 2)

Identified in Olde English Bulldogges

Neuronal Ceroid Lipofuscinosis 10, NCL 10 (CTSD Exon 5)

Identified in Olde English Bulldogges

Ichthyosis (NIPAL4)

Identified in Olde English Bulldogges

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (EE)
K Locus (CBD103)
More likely to have a mostly solid black or brown coat (KBky)
A Locus (ASIP)
Not expressed (ayat)
D Locus (MLPH)
Dark areas of hair and skin are lightened (dd)
B Locus (TYRP1)
Black or gray hair and skin (BB)
Saddle Tan (RALY)
Not expressed (NI)
M Locus (PMEL)
No merle alleles (mm)
H Locus (Harlequin)
No harlequin alleles (hh)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GT)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Coat Texture (KRT71)
Likely straight coat (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (AC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Intermediate (NI)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Lucy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247

Map

A1d

Lucy’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247

Lucy’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Lucy inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Lucy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.