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Lola

Mixed Breed

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“She was a rescue from Tenn. She is allegedly a beagle/spaniel mix.”

This dog has been viewed 473 times and been given 1 wag

Genetic Breed Result

Learn how it’s done

Mixed Breed

28.7% Chihuahua
10.7% Chow Chow
10.0% Cocker Spaniel
9.2% Boston Terrier
8.1% Maltese
7.7% German Shepherd Dog
5.5% Australian Cattle Dog
20.1% Supermutt

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Chihuahua Chihuahua
Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.
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Chow Chow Chow Chow
This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.
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Cocker Spaniel Cocker Spaniel
Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.
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Boston Terrier Boston Terrier
Boston Terriers are lively, intelligent and friendly. Although a small dog, they are strong and sturdy.
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Maltese Maltese
Maltese dogs are confident and friendly toy dogs, that can be high maintenance but boast a beautiful white silky coat.
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German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence.
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Australian Cattle Dog Australian Cattle Dog
A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.
Learn More
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Genetic Stats

Wolfiness: 2.1 % HIGH Learn More
Predicted Adult Weight: 23 lbs Learn More
Genetic Age: 24 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Lola’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Chihuahua
Chow Chow
Cocker Spaniel
Boston Terrier
Maltese
German Shepherd Dog
Australian Cattle Dog
Supermutt

Explore:

Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Chihuahua mix Chow Chow / German Shepherd Dog mix Boston Terrier / Cocker Spaniel mix Chihuahua Maltese mix Chow Chow German Shepherd Dog mix Boston Terrier mix Cocker Spaniel mix Chihuahua Chihuahua Maltese mix Mixed
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Lola’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
2
CARRIER
166
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Lola has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Lola has this …

Not At Risk

Good news! Lola did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Lola does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Lola’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Carrier for 2 genetic conditions

Lola is a carrier for 2 of the genetic diseases that Embark tests for.
What does Carrier mean?

Lola has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Lola ever has children.

Condition List

Von Willebrand Disease Type I
(VWF)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Common Conditions

Good news! Lola tested clear for 23 genetic conditions that are common in her breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Lola.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Lola.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Lola.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Lola.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Chihuahuas, Cocker Spaniels, Malteses, but not Lola.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Seen in Chow Chows, but not Lola.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Chihuahuas, Cocker Spaniels, Australian Cattle Dogs, but not Lola.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Chihuahuas, but not Lola.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Lola.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Australian Cattle Dogs, but not Lola.

Cystinuria Type II-A
(SLC3A1)
Kidney and Bladder

A disease of cystine accumulation, affected dogs are prone to developing cystine kidney and bladder stones, which if caught early can be managed with dietary changes, inc…

Seen in Australian Cattle Dogs, but not Lola.

Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy
(COL4A4 Exon 3)
Kidney and Bladder

This condition causes inappropriate loss of protein in the urine, which leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and excessive thirst a…

Seen in Cocker Spaniels, but not Lola.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Lola.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Lola.

Glycogen Storage Disease Type Ia, Von Gierke Disease
(G6PC)
Multisystem

An early onset type of glycogen storage disease, affected puppies often go to the vet for low energy levels and poor weight gain. Glycogen is the form in which our bodies…

Seen in Malteses, but not Lola.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Lola.

Glycogen storage disease Type VII, Phosphofructokinase deficiency
(PFKM Whippet and English Springer Spaniel Variant)
Multisystem

Affecting an enzyme required for red blood cell and skeletal muscle cell energy production, phosphofructokinase (PFK) deficiency causes red blood cells and skeletal muscl…

Seen in Cocker Spaniels, but not Lola.

Neuronal Ceroid Lipofuscinosis 1
(CLN5 Border Collie Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Lola.

Neuronal Ceroid Lipofuscinosis
(MFSD8)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Chihuahuas, but not Lola.

Neuronal Ceroid Lipofuscinosis
(CLN8)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Lola.

Spinocerebellar Ataxia with Myokymia and/or Seizures
(KCNJ10)
Brain and Spinal Cord

Known as the “oldest” (even reptiles and more ancient species have them!) part of the brain, the cerebellum fine-tunes motor signals from the brain to the muscles, allowi…

Seen in Chihuahuas, but not Lola.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Cocker Spaniels, but not Lola.

Myotonia Congenita
(CLCN1 Exon 23)
Muscular

This condition is characterized by prolonged muscle contraction and stiffness that usually resolves with normal exercise, though physical therapy can be beneficial. The g…

Seen in Australian Cattle Dogs, but not Lola.

Other Conditions: Clear of 143

Lola is clear of 143 other genetic diseases that Embark tests for.

Explore:

Family tree

Traits

Maternal Haplotype

Paternal Haplotype

Jump to:

Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Ee
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
atat
D Locus (Dilute, Blue, Fawn)
Dd
B Locus (Brown, Chocolate, Liver, Red, Dudley)
BB

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
TT
Shedding (MC5R)
TT
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N
Oculocutaneous Albinism Type 2 - OCA2, Doberman Z Factor Albinism (SLC45A2)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NI
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
AA
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

Explore:

Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Lola’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1/13

Map

B1

Lola’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1/13

Lola’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in Shih Tzus, Tibetan Spaniels, Maltese, and village dogs throughout the world including Central and South America, South Asia, and the South Pacific.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Explore:

Family tree

Health

Traits

Paternal Haplotype

This 'Paternal Haplotype' tab is for deep ancestral lineage going back thousands of years.

For recent ancestry—"What breeds did my dog inherit from her mom and dad?"—please refer to the Breed, Family Tree, or Summary tab.

The Paternal Haplotype refers to a dog’s deep ancestral lineage stretching back thousands of years, before there were any distinct breeds of dog. We determine the Paternal Haplotype by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Lola is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

Explore:

Family tree

Health

Traits

Maternal Haplotype