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“Juniper”
Poesia’s Let the Evening Be Gin RE NA NAJ BCAT SWE SCM CGC TKA

Doberman Pinscher

No bio has been provided yet

Place of Birth

Boise, ID, USA

Current Location

Boise, ID, USA

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Registration

American Kennel Club (AKC): WS64808701
Microchip: 990000003271515

Genetic Breed Result

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Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

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Changes to this dog’s profile
  • On 11/6/2019 changed name from "Juniper" to "Poesia’s Let the Evening Be Gin"
  • On 8/14/2019 changed name from "Lilac" to "Juniper"

Health Summary

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Juniper is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Juniper inherited one copy of the variant we tested

How to interpret this result

Juniper has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

ALT Activity

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Juniper inherited one copy of the variant we tested

Why is this important to your vet?

Juniper has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Juniper has this genotype, as ALT is often used as an indicator of liver health and Juniper is likely to have a lower than average resting ALT activity. As such, an increase in Juniper’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS (MYO7A)

Identified in Doberman Pinschers

Dilated Cardiomyopathy, DCM1 (PDK4, Doberman Pinscher Variant 1)

Identified in Doberman Pinschers

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

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Performance

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Through Juniper’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A226

Map

A1e

Poesia’s Let the Evening Be Gin’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A226

Poesia’s Let the Evening Be Gin’s Haplotype

Part of the large A1e haplogroup, we have spotted this haplotype in village dogs in Central and South America and Papua New Guinea. Among the 10 breeds we have detected it in, we see it most frequently in Border Collies, Doberman Pinschers, and Samoyeds.

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Juniper inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Juniper is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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