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“Calypso”
Lightning's Terror of the Sea

Belgian Shepherd

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Place of Birth

Canton, OH, USA

Current Location

Canton, Ohio, USA

From

Canton, OH, USA

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Registration

American Kennel Club (AKC): DN51973201

Genetic Breed Result

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Belgian Sheepdog

The Belgian Sheepdog is one of the four varieties of Belgian Shepherd, though the AKC distinguishes them as their own breed. This active working dog is renowned for its intelligence and drive. If given the opportunity for plenty of physical and mental exercise, the Belgian Sheepdog will astound you with its athleticism and versatility.

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Genetic Stats

Predicted Adult Weight

42 lbs

Genetic Age
40 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Belgian Sheepdog

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Health Summary

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Calypso inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Bald Thigh Syndrome

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Calypso inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Calypso is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Bald Thigh Syndrome?

A cosmetic condition common to sighthounds characterized by hair loss on the thighs. It is caused by a structural abnormality of the hair follicle.

ALT Activity

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Calypso inherited both copies of the variant we tested

Why is this important to your vet?

Calypso has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Calypso's ALT activity above their current, healthy, ALT activity. As an increase above Calypso’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in Belgian Sheepdogs and Belgian Shepherds

Spongy Degeneration with Cerebellar Ataxia 1 (KCNJ10)

Identified in Belgian Sheepdogs and Belgian Shepherds

Spongy Degeneration with Cerebellar Ataxia 2 (ATP1B2)

Identified in Belgian Sheepdogs and Belgian Shepherds

Cardiomyopathy and Juvenile Mortality (YARS2)

Identified in Belgian Sheepdogs and Belgian Shepherds

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Calypso’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B57

Map

B1

Lightning's Terror of the Sea’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B57

Lightning's Terror of the Sea’s Haplotype

Part of the large B1 haplogroup, we have detected this haplotype in Belgian Tervurens, Belgian Malinois, Schipperkes, and village dogs in the Democratic Republic of the Congo.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Calypso inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Calypso is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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