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“Lexi”
Katie's Corgis Lexi

Mixed Ancestry

No bio has been provided yet

Place of Birth

Richland, Washington, USA

Current Location

Glen St Mary, Florida, USA

From

Richland, Washington, USA

This dog has been viewed and been given 41 wags

Registration

Canadian Kennel Club (CKC):
Microchip: 956000013422612

Genetic Breed Result

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Pembroke Welsh Corgi

The Pembroke Welsh Corgi is a small, energetic, herding dog that is good with families.

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Cardigan Welsh Corgi

Though less common than their Pembroke cousins, the Cardigan Welsh Corgi is perfectly suited to move cattle, as well as be a smart, driven companion for the right people. This breed is highly trainable, and often compared to a German Shepherd Dog in drive and attitude. Cardigans have the bark of a much bigger dog!

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DNA Breed Origins

Breed colors:
Pembroke Welsh Corgi
Cardigan Welsh Corgi

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Changes to this dog’s profile
  • On 10/6/2020 changed name from "Katie's Corgi's Lexi" to "Katie's Corgis Lexi"
  • On 8/2/2020 changed name from "Lexi" to "Katie's Corgi's Lexi"
Here’s what Lexi’s family tree may have looked like.
Katie's Corgis Lexi
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Pembroke Welsh Corgi mix Pembroke Welsh Corgi mix Pembroke Welsh Corgi Cardigan Welsh Corgi / Pembroke Welsh Corgi mix Pembroke Welsh Corgi Pembroke Welsh Corgi / Cardigan Welsh Corgi mix Pembroke Welsh Corgi Pembroke Welsh Corgi Cardigan Welsh Corgi Pembroke Welsh Corgi Pembroke Welsh Corgi Pembroke Welsh Corgi Pembroke Welsh Corgi Cardigan Welsh Corgi
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Lexi’s breed mix.
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Health Summary

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Lexi is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Lexi inherited both copies of the variant we tested

How to interpret this result

Lexi has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Dilated Cardiomyopathy, DCM2

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Lexi inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Lexi will develop this condition.

Scientific Basis

Dogs with Lexi’s breeds have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Lexi developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Lexi inherited one copy of the variant we tested

Why is this important to your vet?

Lexi has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Lexi has this genotype, as ALT is often used as an indicator of liver health and Lexi is likely to have a lower than average resting ALT activity. As such, an increase in Lexi’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

X-linked Severe Combined Immunodeficiency, X-SCID (IL2RG, Corgi Variant)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Degenerative Myelopathy, DM (SOD1A)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Exercise-Induced Collapse, EIC (DNM1)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Lexi’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A263

Map

A1a

Katie's Corgis Lexi’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A263

Katie's Corgis Lexi’s Haplotype

Part of the large A1a haplogroup, we see this haplotype most frequently in Cardigan Welsh Corgis and Pembroke Welsh Corgis.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Lexi inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Lexi is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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