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Le Papillon Ravissant Kristian

Papillon

“Kristian is a drop ear Papillon ( Phalene) that came over to the US from Russia. He has tons of energy and an outgoing personality. He loves to climb things, including me!”

Place of Birth

Barnaul, Russia

Current Location

East Windsor, New Jersey, USA

From

Barnaul, Russia

This dog has been viewed and been given 2 wags

Registration

American Kennel Club (AKC): TS43508701

Genetic Breed Result

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Papillon

The Papillon, also called the Continental Toy Spaniel, is a breed of dog of the Spaniel type.

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Health Summary

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Le Papillon Ravissant Kristian is at increased risk for two genetic health conditions.

Von Willebrand Disease Type I, Type I vWD

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Le Papillon Ravissant Kristian inherited one copy of the variant we tested

How to interpret this result

Le Papillon Ravissant Kristian has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Intervertebral Disc Disease (Type I)

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Le Papillon Ravissant Kristian inherited one copy of the variant we tested

What does this result mean?

Follow-up by our experts indicates that this genetic variant is associated with an increase to Le Papillon Ravissant Kristian’s risk for developing Intervertebral Disc Disease (Type I).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Le Papillon Ravissant Kristian have not yet been the focus of research studies, our data indicates that Le Papillon Ravissant Kristian is likely to be at increased risk.

Impact on Breeding

While further investigation is warranted to determine the clinical presentation and penetrance in Le Papillon Ravissant Kristian’s breed, we recommend taking this genetic result into account when making breeding decisions.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency (F7 Exon 5)

Identified in Papillons

Progressive Retinal Atrophy, PRA1 (CNGB1)

Identified in Papillons

Progressive Retinal Atrophy, crd4/cord1 (RPGRIP1)

Identified in Papillons

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

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Through Le Papillon Ravissant Kristian’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Le Papillon Ravissant Kristian’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Le Papillon Ravissant Kristian’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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Through Le Papillon Ravissant Kristian’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.2

Map

A1b

Le Papillon Ravissant Kristian’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.2

Le Papillon Ravissant Kristian’s Haplotype

Part of the A1b haplogroup, this haplotype is found in Papillons and village dogs in Central America, Africa, and Eurasia.

Great Danes and Pomeranians have this in common!

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