Venn diagram

Compare your dogs to Leo The Lion Select one to begin:

“Leo The Lion”
Amore Mio Club Leo Binary Celtic Star

Mixed Ancestry

“TATTOO # OKKC 042 GOLDDUST YORKSHIRE TERRIER imported from Russia”

This dog has been viewed and been given 0 wags

Registration

N/A : RKD 11225
Microchip: 643094800019515

Genetic Breed Result

Loading...

Yorkshire Terrier

Petite but proud, the Yorkshire terrier is a popular toy breed with a silky, low-shedding coat.

Learn More

West Highland White Terrier

Westies are confident and friendly terriers, with an intelligent and curious mind that requires both mental and physical stimulation to become a well-rounded dog.

Learn More

Maltese

Maltese dogs are confident and friendly toy dogs, that can be high maintenance but boast a beautiful white silky coat.

Learn More

Loading...

Start a conversation! Message this dog’s owner.

Loading...

DNA Breed Origins

Breed colors:
Yorkshire Terrier
West Highland White Terrier
Maltese

Explore

Health Summary

danger icon

Leo The Lion is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

danger icon

Leo The Lion inherited one copy of the variant we tested

What does this result mean?

Follow-up by our experts indicates that this genetic variant is associated with an increase to Leo The Lion’s risk for developing Intervertebral Disc Disease (Type I).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Leo The Lion have not yet been the focus of research studies, our data indicates that Leo The Lion is likely to be at increased risk.

Impact on Breeding

While further investigation is warranted to determine the clinical presentation and penetrance in Leo The Lion’s breeds, we recommend taking this genetic result into account when making breeding decisions.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

warn icon

Leo The Lion inherited one copy of the variant we tested

Why is this important to your vet?

Leo The Lion has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Leo The Lion has this genotype, as ALT is often used as an indicator of liver health and Leo The Lion is likely to have a lower than average resting ALT activity. As such, an increase in Leo The Lion’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

good icon

Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in West Highland White Terriers

Pyruvate Kinase Deficiency (PKLR Exon 10, Terrier Variant)

Identified in West Highland White Terriers

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Yorkshire Terriers

Primary Lens Luxation (ADAMTS17)

Identified in Yorkshire Terriers

Glycogen Storage Disease Type IA, Von Gierke Disease, GSD IA (G6PC, Maltese Variant)

Identified in Malteses

Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5, Terrier Variant)

Identified in West Highland White Terriers

Craniomandibular Osteopathy, CMO (SLC37A2)

Identified in West Highland White Terriers

Additional Genetic Conditions

good icon

Explore

Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

Loading...

Explore

Through Leo The Lion’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18/19/20/21/27/36/94/109

Map

A1b

Amore Mio Club Leo Binary Celtic Star’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18/19/20/21/27/36/94/109

Amore Mio Club Leo Binary Celtic Star’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in over 25 countries across the world. We have detected this haplotype in lots of breeds, and it occurs most commonly in German Shepherd Dogs, Maltese, English Springer Spaniels, and English Setters.

A1b is the most common haplogroup found in German Shepherds.

Loading...

Explore

Through Leo The Lion’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.2

Map

A1a

Amore Mio Club Leo Binary Celtic Star’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.2

Amore Mio Club Leo Binary Celtic Star’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, Norfolk Terriers, Silky Terriers, and Norwich Terriers.

Dogs with A1a lineage travelled during European Colonial times.

Loading...

Explore