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“Lena”
Sterre Jansje v.'t Hondsdraf

Stabyhoun

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“Lena is een eigenzinnige maar super lieve dame”

Place of Birth

Rotterdam, Nederland

Current Location

Putten, Nederland

From

Rotterdam, Nederland

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Registration

N/A : 3155388

Genetic Breed Result

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Stabyhoun

Renowned for its peaceful disposition, the Stabyhoun is a soft-mouthed retriever, a fine pointer, excellent tracker, and a good watchdog.

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Changes to this dog’s profile
  • On 11/17/2020 changed name from "Lena" to "Sterre Jansje v.'t Hondsdraf"

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Health Summary

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Lena is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Lena inherited both copies of the variant we tested

How to interpret this result

Lena has two copies of a variant in the vWF gene and is at risk for developing Type I vWD. Please consult your veterinarian to discuss further diagnostics as well as monitoring and care options for Lena.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Degenerative Myelopathy, DM

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Lena inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Lena is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Clinical Tools

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Coat Color

Coat Color

Other Coat Traits

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Body Size

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Through Lena’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1c

Map

B1

Sterre Jansje v.'t Hondsdraf’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1c

Sterre Jansje v.'t Hondsdraf’s Haplotype

Part of the large B1 haplogroup, we have detected this haplotype in Mexico and Lebanon village dogs. Among the 12 breeds that we have spotted this haplotype in, it occurs most frequently in Border Collies, Australian Shepherd Dogs, and West Highland white Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Lena inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Lena is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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