Baylene inherited one copy of the variant we tested
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Place of Birth
USA
Current Location
USA
From
USA
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Registration
American Kennel Club
(AKC):
SS25254601
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Health Summary
Baylene inherited one variant that you should learn more about.
And one variant that you should tell your vet about.
Ichthyosis, ICH1
What does this result mean?
This result should not impact Baylene’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.
Impact on Breeding
Your dog carries this variant and will pass it on to ~50% of her offspring.
What is Ichthyosis, ICH1?
This skin disorder gets its name from the thick, darkly pigmented scales of skin ("ichthys" is Greek for "fish") that affected dogs display over most areas of the body, not including the head or extremities.
ALT Activity
Baylene inherited one copy of the variant we tested
Why is this important to your vet?
Baylene has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Baylene has this genotype, as ALT is often used as an indicator of liver health and Baylene is likely to have a lower than average resting ALT activity. As such, an increase in Baylene’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
Progressive Retinal Atrophy, prcd (PRCD Exon 1)
Identified in Golden Retrievers
Variant not detected
Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1 (SLC4A3)
Identified in Golden Retrievers
Variant not detected
Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)
Identified in Golden Retrievers
Variant not detected
Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 Deletion, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Degenerative Myelopathy, DM (SOD1A)
Identified in Golden Retrievers
Variant not detected
Muscular Dystrophy (DMD, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Congenital Myasthenic Syndrome, CMS (COLQ, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Dystrophic Epidermolysis Bullosa (COL7A1, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected
Osteogenesis Imperfecta (COL1A1, Golden Retriever Variant)
Identified in Golden Retrievers
Variant not detected