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“Tyrion”
Lara's Radost Imperial Diamond

Borzoi

No bio has been provided yet

Place of Birth

New Jersey, USA

Current Location

526 Broken Arrow Lane, Spring Creek, NV, USA

From

405 Oak Tree Avenue, South Plainfield, NJ, USA

This dog has been viewed and been given 0 wags

Registration

American Kennel Club (AKC): HP63742203

Genetic Breed Result

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Borzoi

The Borzoi is a large, slender sighthound breed from Russia. Elegant and regal, they have powerful builds that enable them to hunt fast-moving animals like rabbits and foxes. Some of them were even used to hunt wolves in their homeland. Borzoi are affectionate dogs and true canine athletes who love to give chase. Because they’re built for speed, many excel at lure coursing.

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Health Summary

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Tyrion inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Tyrion inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Tyrion’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Tyrion is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Bald Thigh Syndrome

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Tyrion inherited both copies of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Tyrion will develop Bald Thigh Syndrome.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Tyrion's breed have been studied to know whether or not this variant will increase Tyrion's risk of developing this disease.

Impact on Breeding

Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Bald Thigh Syndrome in your breeding program and related dogs.

What is Bald Thigh Syndrome?

A cosmetic condition common to sighthounds characterized by hair loss on the thighs. It is caused by a structural abnormality of the hair follicle.

ALT Activity

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Tyrion inherited one copy of the variant we tested

Why is this important to your vet?

Tyrion has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Tyrion has this genotype, as ALT is often used as an indicator of liver health and Tyrion is likely to have a lower than average resting ALT activity. As such, an increase in Tyrion’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

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Body Size

Body Size

Performance

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Through Tyrion’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A424

Map

A1d

Lara's Radost Imperial Diamond’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A424

Lara's Radost Imperial Diamond’s Haplotype

Part of the A1d haplogroup, this haplotype occurs most frequently in American Pit Bull Terriers, Barbets, and Staffordshire Terriers.

The vast majority of Rottweilers have the A1d haplogroup.

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Through Tyrion’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.38

Map

A1a

Lara's Radost Imperial Diamond’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.38

Lara's Radost Imperial Diamond’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Dogs with A1a lineage travelled during European Colonial times.

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