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Lady Merle

Mixed Ancestry

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“Lady is a smart and agile girl with character. She is an American Corgi with the best characteristics of both corgi breeds.”

Place of Birth

Olympia, WA, USA

Current Location

Lakewood, Washington, USA

From

Olympia, WA, USA

This dog has been viewed and been given 52 wags

Registration

Continental Kennel Club (CKC): AKM05155253
Microchip: 956000010774892

Genetic Breed Result

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Cardigan Welsh Corgi

Though less common than their Pembroke cousins, the Cardigan Welsh Corgi is perfectly suited to move cattle, as well as be a smart, driven companion for the right people. This breed is highly trainable, and often compared to a German Shepherd Dog in drive and attitude. Cardigans have the bark of a much bigger dog!

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Pembroke Welsh Corgi

The Pembroke Welsh Corgi is a small, energetic, herding dog that is good with families.

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Start a conversation! Message this dog’s owner.

Genetic Stats

Predicted Adult Weight

27 lbs

Genetic Age
33 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Cardigan Welsh Corgi
Pembroke Welsh Corgi

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Health Summary

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Lady Merle is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Lady Merle inherited both copies of the variant we tested

How to interpret this result

Lady Merle has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Degenerative Myelopathy, DM

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Lady Merle inherited one copy of the variant we tested

What does this result mean?

This result should not impact Lady Merle’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Lady Merle inherited one copy of the variant we tested

Why is this important to your vet?

Lady Merle has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Lady Merle has this genotype, as ALT is often used as an indicator of liver health and Lady Merle is likely to have a lower than average resting ALT activity. As such, an increase in Lady Merle’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

X-linked Severe Combined Immunodeficiency, X-SCID (IL2RG, Corgi Variant)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Exercise-Induced Collapse, EIC (DNM1)

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Lady Merle’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A263

Map

A1a

Lady Merle’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A263

Lady Merle’s Haplotype

Part of the large A1a haplogroup, we see this haplotype most frequently in Cardigan Welsh Corgis and Pembroke Welsh Corgis.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Lady Merle inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Lady Merle is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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