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Kyrös

Mixed Breed

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“Kyrös, also known as 'That PNW Dog' and the 'King of the Pacific Northwest'. Male rescue husky from a bad situation.”

This dog has been viewed 846 times and been given 4 wags

Genetic Breed Result

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Mixed Breed

79.1% Siberian Husky
8.2% Keeshond
7.5% Collie
5.2% Labrador Retriever
Siberian Husky Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
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Keeshond Keeshond
The Keeshond is one of the friendlies dogs out there. They appear to have a permenant smile on their face. They were originally bred as watchdogs in Holland, but now serve a lovable companions in the home.
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Collie Collie
Collies are attractive herding dogs, boasting a beautiful coat while being highly intelligent. They also make for extremely loyal and sweet family pets.
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Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
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Genetic Stats

Wolfiness: 2.9 % HIGH Learn More
Predicted Adult Weight: 71 lbs Learn More
Genetic Age: 54 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Kyrös’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Siberian Husky
Keeshond
Collie
Labrador Retriever

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Siberian Husky mix Siberian Husky mix Siberian Husky Siberian Husky / Labrador Retriever mix Siberian Husky Siberian Husky / Keeshond mix Siberian Husky Siberian Husky Siberian Husky Labrador Retriever mix Siberian Husky Siberian Husky Siberian Husky Keeshond mix
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Kyrös’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
0
CARRIER
165
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Kyrös has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kyrös has thi…

Not At Risk

Good news! Kyrös did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Kyrös does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Kyrös’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Kyrös is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Kyrös tested clear for 21 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Collies, but not Kyrös.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Labrador Retrievers, but not Kyrös.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Seen in Labrador Retrievers, but not Kyrös.

Cyclic Neutropenia, Gray Collie Syndrome
(AP3B1 Exon 20)
Blood

This is a disease of neutrophil, a type of white blood cell, production, where the number of circulating neutrophils drops precipitously, leaving dogs prone to bacterial …

Seen in Collies, but not Kyrös.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Kyrös.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Kyrös.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Kyrös.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Kyrös.

Collie Eye Anomaly, Choroidal Hypoplasia
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Seen in Collies, but not Kyrös.

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in Labrador Retrievers, but not Kyrös.

Macular Corneal Dystrophy (MCD)
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Seen in Labrador Retrievers, but not Kyrös.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Kyrös.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Siberian Huskys, Keeshonds, Collies, Labrador Retrievers, but not Kyrös.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Kyrös.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as 1 month, the sy…

Seen in Labrador Retrievers, but not Kyrös.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Labrador Retrievers, but not Kyrös.

Myotubular Myopathy 1, X-linked Myotubular Myopathy
(MTM1)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Kyrös.

Congenital Myasthenic Syndrome
(COLQ)
Neuro-muscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Seen in Labrador Retrievers, but not Kyrös.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Kyrös.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Seen in Labrador Retrievers, but not Kyrös.

Skeletal Dysplasia 2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Kyrös.

Other Conditions: Clear of 144

Kyrös is clear of 144 other genetic diseases that Embark tests for.

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Family tree

Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
EE
K Locus (Dominant Black)
kyky
A Locus (Agouti, Sable)
awaw
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red, Dudley)
Bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GT
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N
Oculocutaneous Albinism Type 2 - OCA2, Doberman Z Factor Albinism (SLC45A2)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
Dup/Dup

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

Explore:

Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Kyrös’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A241

Map

A1e

Kyrös’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A241

Kyrös’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs most commonly in village dogs up in Alaska.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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Family tree

Health

Traits

Paternal Haplotype

Through Kyrös’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.4

Map

A1b

Kyrös’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.4

Kyrös’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs in North America and Africa. As for breeds, it occurs most frequently in Miniature Pinscher, Great Dane, and Poodle.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

Explore:

Family tree

Health

Traits

Maternal Haplotype